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How often do you come across a method development problem that proves difficult to solve?
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Contact Us
Click here to contact Kate Mosford, managing editor.
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15 March 2013
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| In this Issue |
Identifying “Known Unknowns” in Commercial Products by MS
A systematic approach for thee identification of nontargeted species using nominal and accurate mass data searching both mass spectral and “spectra-less” databases is described. More... |
GC–MS Detects Stress Levels
Breath may be an indicator of stress levels according to a study published in the Journal of Breath Research.1The breath samples of 22 individuals were analysed by performing thermal desporption–gas chromatography–mass spectrometry (TD–GC–MS) to pinpoint six stress sensitive compounds. More... |
Waters Opens Solution Centre in Singapore
Waters Corporation (Massachusetts, USA) has announced the opening of a Solution Centre based within the Singapore Science Park II (Singapore). The company aims to further strengthen their support of the developing biomedical sector in the region. More... |
| Current features |
Troubleshooting GC Gas Supply, Sample Preparation and Inlets
An excerpt from LCGC’s e-learning tutorial on GC troubleshooting and maintenance at CHROMacademy.com. More... |
Simultaneous Qualitative and Quantitative Proteomics Using Tandem Mass Spectrometry
Quantitative proteomics aims to provide large-scale qualitative and quantitative data about every protein in a biological sample. However, drawbacks associated with current techniques can make it difficult to generate the data required. Research scientists have recently developed a new approach that allows highly multiplexed high-resolution MRM quantitation of most of the detectable proteins in a sample in a single analysis. More... |
| Multimedia |
| Validation of an Automated, Qualitative Pesticide Screening Solution according to EU SANCO/12495/2011 AQC Guidelines |
| Ion Exchange Mechanisms in SPE: The Ultimate in Selectivity |
| Application Protocol for EPA Method 539 |
Need GC Troubleshooting Help?
CHROMacademy announces the launch of the interactive GC Troubleshooter, sponsored by Thermo Scientific
Building on the success of our ground breaking HPLC Troubleshooter, we are excited to announce the GC version. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It’s completely free - so if you haven't tried our troubleshooter before you're in for a surprise!
 http://bit.ly/GC_troubleshooting |
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| Product Profiles
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| Agilent Technologies |
 Succeed from Sample Prep to Preparation
Agilent offers a complete portfolio of Fast LC columns—conventional HPLC or UHPLC and biocolumns in reversed phase, size exclusion, ion exchange and affinity—plus the sample prep chemistries you need to perfect your analysis. Bring your separations together with Agilent LC tools and resources at, www.agilent.com/chem/navigator. |
| NIBRT |
National Institute for Bioprocessing Research and Training (NIBRT)
Advanced biopharmaceutical training in the most cutting-edge analytical methods and techniques: NIBRT's state-of-the-art facility in Dublin, Ireland provides comprehensive, innovative training solutions for academia and industry. Read more
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| Porvair Sciences |
 Reduce the Cost of Your Protein Precipitation Sample Preparation
Comprising four p3 protein precipitation plates and four 1ml deep well collection plates (colour coded in red or blue polypropylene) the Combipack from Porvair Sciences provides all the elements you require to undertake protein precipitation separations at a very affordable price.  Read more
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| Waters |
Waters NuGenesis® 8 is a comprehensive data management and workflow solution that combines data repository, E-lab notebook, sample management, laboratories inventories, and e-record lifecycle management to provide easily accessible data. Read more
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| Wyatt Technology |
 First Refractive Index Detector for UHPLC
Wyatt Technology announces the immediate availability of the Optilab UT-rEX (UHPLC refractometer with EXtended range), the first RI detector specifically designed for use with UHPLC systems using columns packed with small beads.  Read more
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| Thermo Fisher
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Essential to the development of biotherapeutics is ability to quickly and accurately assess product quality—including factors such as sequence integrity, glycan heterogeneity, and purity—at each step. Thermo Scientific workflows for intact-protein analysis enable these assessments early in the development process without the effort of complete characterization and allowing you to make better, faster decisions about how to proceed with your biotherapeutic development. Learn More
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