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September 12, 2013
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The LCGC Blog

The LCGC Blog: From HPLC to LC–MS: Mobile-Phase Composition is the Main Consideration
Researchers coupling high performance liquid chromatography to mass spectrometry face the challenge of segregating the ionized, typically nonvolatile analytes from a large amount of solvent, and the mobile phase is an important component in the process. LCGC Blog editor Kevin Schug discusses factors to consider when choosing a mobile phase for LC–MS. More...
 
Quantify Organic Compounds in Water
Explore quick and cost-effective solutions using online-SPE to quantify trace levels of emerging organic contaminants in water. Learn about automated sample prep and enriching analytes before an LC/MS analysis through our application notes and videos. Gain instant access to our complimentary Online-SPE information toolkit.
 
Featured News

Watermelon Juice Enhances Athletic Performance More Than Pharmacological Standard
Experts in the food industry are always searching for natural sources of bioactive compounds to develop products that enhance athletic performance. A new study has suggested that drinking watermelon juice may alleviate muscle ache experienced by many athletes, and non-athletes, following a period of exercise. The study published in the Journal of Agricultural and Food Chemistry showed that naturally high levels of L-citrulline in watermelon juice may be more effective than pharmacological supplements. Click here.
 
Rethink Imaging Mass Spectrometry
Protea’s LAESI® DP-1000 Direct Ionization System revolutionizes the way you approach imaging mass spectrometry. This powerful platform analyzes biomolecules in your sample WHERE they are and AS they are. The LAESI DP-1000 unlocks the power of your mass spec workflow, providing you with molecular distribution maps, eliminating sample prep, and offering you a broad range of new sample types. Learn more@ proteabio.com/LAESI.
 
LC Troubleshooting

Need Help With LC Troubleshooting?
A free interactive LC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. Click here.
 
Download LCGC’s New E-Book: Innovations in Environmental Analysis
No matter what type of environmental testing you do, you need the latest methods. This new special issue is here to help, by bringing together vital information on methods for environmental analysis.
Sponsored by Thermo Scientific Download Today.
 
Featured Product
New Viscotek SEC-MALS 20
The Viscotek SEC-MALS 20 multi-angle light scattering detector measures absolute molecular weight and size (Rg) of proteins and polymers. Its 20 detector array and vertical flow cell ensure exceptional accuracy.
Learn More.
 
New Webcasts
Recent Developments in Protein Glycosylation Analysis by HPLC with Charged Aerosol and Mass Spectrometric Detection
Tuesday, September 17, 2013
8:00 am PDT/ 11:00 am EDT/ 16:00 BST/ 17:00 CEDT.
Need a competitive edge for the LC analysis of glycans? Tune into this web seminar to learn how to overcome the limitations of conventional LC fluorescence labeling by using charged aerosol detection in combination with MS for direct measurement and characterization of native glycans.
 
Preparing Your Analytical Laboratory for a Regulatory Audit
Friday, September 20 , 2013
10:00 AM EDT; 3:00 PM BST.
Effectively prepare your analytical laboratory for a regulatory audit by joining us for this free, webcast. Learn tips and strategies to get your team ready for success in this critical activity.
 
Preparing Your Analytical Laboratory for a Regulatory Audit
Tuesday, September 24, 2013
11:30 AM IST, 2:00 PM SGT, 2:00 PM CST, 3:00 PM JST, 4:00 PM AEST.
Effectively prepare your analytical laboratory for a regulatory audit by joining us for this free, webcast. Learn tips and strategies to get your team ready for success in this critical activity.
 
Get More from Your Analytical Systems – Improve Utilization, Reduce Operating Costs and Focus Future Capital Purchases to improve Efficiency
Thursday, September 26, 2013
5:00 AM EDT ; 11:00 AM CET.
Budgets are tight – Learn how to reduce analytical system operating costs and increase system utilization.
 
Separation of Monoclonal Antibody Monomer from its High and Low Molar Mass Impurities Using Size Exclusion and Reversed Phase Chromatography
Tuesday, October 1, 2013
2:00 PM EDT.
Attend this webinar to learn about the latest developments in monoclonal antibody (mAb) analysis using size exclusion and reversed phase chromatography. In this seminar, we will explain the best methods for the separation of a mAb from both its high and low molar mass impurities.
 
Editors’ Series: Optimizing Your Extraction by Removing Uncertainty
Wednesday, October 2, 2013
9:00 am EDT/ 2:00 PM BST/ 3:00 PM CEST.
Optimization of the extraction process ensures better quality data. Is this statement really true? We will look at the evidence and present details on how to get the best out of the whole assay.
 
Editors’ Series: Fundamentals, Optimization and Practical Aspects of UHPLC: Series 1:  Fundamentals, Optimization and Practical Aspects of UHPLC
Wednesday, October 30, 2013
9:00 AM EDT/ 1:00PM GMT/ 2:00PM CET.
A scientific, unbiased series of webinars on UHPLC. This three-part series of "must-attend" events for those who have heard about, or use UHPLC, and want to know more.
 
Using New SPE and LC Columns to Improve Your Results Quality and Workflow Efficiency in Regulated Bioanalysis
Thursday, October 31, 2013
8:00 am PDT/ 11:00 am EDT/ 15:00 GMT/ 16:00 CET.
In this webinar, we will discuss how the combination of next-generation SPE technology and solid core LC columns delivers improved efficiency to regulated bioanalytical workflows. It will be demonstrated that the combination provides higher levels of cleanliness, reproducibility, throughput, sensitivity and quality of results, with lower failure rates.
 
Editors’ Series: Fundamentals, Optimization and Practical Aspects of UHPLC: Series 2: Optimization of UHPLC Systems and Column Technology
Thursday, November 7, 2013
9:00 PM EST/ 2:00PM GMT/ 3:00PM CET.
A scientific, unbiased series of webinars on UHPLC. This three-part series of "must-attend" events for those who have heard about, or use UHPLC, and want to know more.
 
Editors’ Series: Fundamentals, Optimization and Practical Aspects of UHPLC: Series 3:  Practical Aspects of UHPLC
Tuesday, December 3, 2013
9:00 PM EST/ 2:00PM GMT/ 3:00PM CET.
A scientific, unbiased series of webinars on UHPLC. This three-part series of "must-attend" events for those who have heard about, or use UHPLC, and want to know more.
 
 
 
Upcoming Events

16–18 September 2013
Applied Pharmaceutical Analysis
Boston, MA
» Visit the website
 
20 September–4 October 2013
SciX 2013 - The Great SCIentific eXchange
Milwaukee, WI USA
» Visit the website
 
23–25 September 2013
Polyurethanes 2013
Phoenix, AZ
» Visit the website
 
23–26 September 2013
10th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry
Boston, MA
» Visit the website
 
24–26 September 2013
Analitica South America
Sao Paulo, SP., Brazil
» Visit the website
 
24–26 September 2013
Analytica China
Shanghai, China
» Visit the website
 
25–28 September 2013
New Achievements in Chromatography – 19th International Symposium on Separation Sciences
Porec, Croatia
» Visit the website
 
6–9 October 2013
20th International Symposium on Electro- and Liquid- Phase-Separation Techniques(ITP2013)
Puerto de la Cruz, Tenerife, Canary Islands (Spain)
» Visit the website
 
8–11 October 2013
XIII Scientific Meeting of the Spanish Society of Chromatography & Related Techniques
Puerto de la Cruz, Tenerife, Canary Islands (Spain)
» Visit the website
 
22–24 October 2013
Validation Week
San Diego, CA
» Visit the website
 
5–8 November 2013
RAFA 2013 6th International Symposium on Recent Advances in Food Analysis
Prague, Czech Republic
» Visit the website
 
6–7 November 2013
Lab Innovations 2013
Birmingham, England
» Visit the website
 
18–20 November 2013
Eastern Analytical Symposium & Exposition
Somerset, NJ
» Visit the website
 
3–5 December 2013
QbD Quality by Design
Philadelphia, PA
» Visit the website
 
3–5 December 2013
Lab Compliance Week
Philadelphia, PA
» Visit the website
 
3–5 December 2013
Stability Testing, Part of Lab Compliance Week
Philadelphia, PA
» Visit the website