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The LCGC Blog |
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The LCGC Blog: An Excel Tutorial for Modeling Chromatographic Separations
Chromatography can be approximated by a series of equilibrium events between the mobile phase and stationary phase. Here, LCGC Blog editor Kevin Schug discusses an exceptional spreadsheet macro written by an undergraduate researcher that helps users visualize the development of chromatographic separations. More...
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Are you using the right vial?
By answering 4 simple questions, the Waters Vials Selector suggests the best vial for your application. Using the most appropriate vial for your system, sample volume, and detection method will get your analysis off to the right start. Find out more. |
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Podcast Interview |
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CE–MS for proteomics applications
An interview with Norman Dovichi, winner of the 2013 ANACHEM Award. This interview is part of the 2013 podcast series presented in collaboration with the Federation of Analytical Chemistry and Spectroscopy Societies (FACSS), in connection with SciX 2013, the federation’s North American conference. For more podcasts in this series from 2013 and 2012 Click here. |
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Succeed from Sample Prep to Separation
Agilent offers a complete portfolio of Fast LC columns—conventional HPLC or UHPLC and biocolumns in reversed phase, size exclusion, ion exchange and affinity—plus the sample prep chemistries you need to perfect your analysis. Bring your separations together with Agilent LC tools and resources at www.agilent.com/chem/navigator. |
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Featured News |
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Life Technologies To Advance Food Safety in Collaboration with FDA
Life Technologies (Carlsbad, California) has announced the signing of a five-year collaboration with the Food and Drug Administration (FDA). The collaboration will see Life Technologies working with the FDA to develop food safety testing of two foodborne pathogens, E.coli and Salmonella. This follows the announced acquisition of Life Technologies by Thermo Fisher Scientific (Waltham, Massachusetts) in April. More... |
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Simplify your Method Development
The NEW online Oasis Method Development Tools from Waters Corporation are now available. Based on the customers’ sample requirements, the Oasis Tools recommend the optimized solid-phase extraction(SPE) protocol to help you calculate matrix effects and develop robust sample preparation methods in minutes, with high recovery and reproducibility for your LC/MS applications. Try them now |
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Waters Sponsors Clinical Chemistry Fellowship at University of California
Waters (Milford, Massachusetts) has announced the sponsorship of a new, two-year postdoctoral Clinical Chemistry Fellowship at the University of California, San Diego School of Medicine (San Diego, California).
Fellows will be prepared for directorship positions at medical schools or hospital-based clinical chemistry laboratories. They will receive training in classical chemistry, laboratory administration, and research practices. In addition, fellows will collaborate with the California Poison Control Center and the UC San Diego Medical Toxicology program. More... |
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TRUST THE INDUSTRY LEADER
Offering the industry’s broadest selection of standard and custom fused silica capillary tubing, Polymicro products provide unmatched design flexibility and the tightest tolerances available. Our 1/32” OD capillary tubing is now available in pre-cut lengths of 10, 15, and 25 cm. For products you can trust, turn to Polymicro from Molex. |
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Articles |
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Characterizing Phenolic Compounds in Fava Beans
Fava beans are a good source of polyphenols and are located in different parts of the plant. Phenolic compounds are thought to contribute to the overall antioxidant activities of plant foods. However, there is a lack of information on the phenolic composition of the seeds (beans) of some edible varieties. This has led a team of researchers based in Chile and Spain to use high performance liquid chromatography (HPLC) to identify the composition of a variety of immature fava seeds. More... |
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Monitor Your Chromatography System Anytime, Anywhere
Empower® Mobile, a new capability of Waters® Empower 3 Chromatography Data Software, gives you wireless access to Empower from a tablet or smartphone, making it easier to know what's happening in your laboratory no matter where you are. Monitor system status, perform routine system administration tasks, and review and signoff reports. Learn more |
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Oil Sheen Mystery Solved by GC–GC Analysis
Comprehensive two-dimensional gas chromatography (GC–GC) has been performed to identify the origins of a mysterious oil sheen in the Gulf of Mexico, first reported in September 2012. The results have been published in the journal Environmental Science and Technology by researchers from the University of California (California, USA) and the Woods Hole Oceanographic Institute (WHOI) (Woods Hole, Massachusetts). More... |
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Simplified HILIC separations from a world leader in HILIC
New, eHILIC chemistry from The Nest Group, Inc. addresses both acidic and basic, polar analyte separation challenges. Whether the goal is to reduce their interaction or enhance it, our ERLIC capability facilitates separations by polar differences. Try our ERLIC separation approaches today! The Nest Group, Inc. - "Not Just Columns ... Answers!". |
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GC Troubleshooting |
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Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. More... |
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A Powerful Solution for Organization-Wide Scientific Information Search
Waters® Paradigm Scientific Search offers the solution to search for scientifically relevant information across an organization by spanning information silos, performing searches based on science objects, and adding structure to unstructured data. Learn more |
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Featured Products |
New Preparative Aqueous SEC/GFC Columns
Yarra™ ultra-high resolution aqueous size exclusion (SEC)/ gel filtration (GFC) columns for proteins and peptides just expanded to include a preparative solution for purification, desalting, and characterization. Learn more |
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Sensitive, Ultrafast LCMS
Utilizing patented ultrafast technology, Shimadzu's LCMS-2020 mass spectrometer offers faster measurements and higher detection sensitivity for quicker and more accurate detection of trace impurities in a variety of applications. Learn more |
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Introducing new TSKgel® SW mAB Columns
Tosoh Bioscience is proud to introduce two new additions to the renowned TSKgel SW line of size exclusion columns. These columns are specifically designed for optimum monoclonal antibody analysis and include the TSKgel SuperSW mAb HR, for the high resolution analysis of mAb monomers and dimers, and TSKgel UltraSW Aggregate for the analysis of multimers and aggregates. Visit the Tosoh Bioscience website to learn how to take your mAb analysis to the next level. Learn more |
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SEC-MALS Detector
Based on Wyatt Technology’s family of multi-angle light scattering detectors, the new DAWN HELEOS-II boasts 18-angles of detection for the greatest sensitivity for absolute molecular weight and size determinations of polymers and biopolymers in solution. It may be connected in series to any chromatographic system in order to determine absolute molar masses without the use of reference standards or column calibration. Learn more |
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New Webcasts |
Analysis of Post-translational Modifications Using LC–MS-MS
Thursday, August 22, 2013
8:00 am PDT/11:00 am EDT/16:00BST/17:00 CEDT.
In this session, Dr Duncan Smith and Dr John Griffiths (MS-Insight Ltd and Manchester University) explain the principles behind the analysis of a number of key post-translational modifications (PTMs) using LC-MS/MS techniques. |
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Recent Developments in Protein Glycosylation Analysis by HPLC with Charged Aerosol and Mass Spectrometric Detection
Tuesday, September 17, 2013
8:00 am PDT/ 11:00 am EDT/ 16:00 BST/ 17:00 CEDT.
This web seminar will discuss promising improvements to glycosylation analysis that couple unique HPLC stationary phases with direct measurement of glycans by charged aerosol detection and with flow-splitting for simultaneous mass spectrometry MS-MS detection. These strategies avoid problematic O-linked glycan degradation (“peeling”) associated with some other quantitative methods, and employs optimal conditions for heightened characterization using additional offline MS techniques for characterization. |
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Get More from Your Analytical Systems – Improve Utilization, Reduce Operating Costs and Focus Future Capital Purchases to improve Efficiency
Thursday, September 26, 2013
5:00 AM EDT ; 11:00 AM CET.
Every Laboratory must balance analytical system capacity, workload and throughput with operating and capital expense constraints. Often the information needed to drive spending decisions is subjective, limited or both. This Webinar will demonstrate how to objectively inform your decision-making around asset utilization, consumables usage, service event planning and capital expenditure, leading to increased efficiency in your laboratory. |
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Upcoming Events |
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25–28 August 2013
AOAC 127th Annual Meeting & Exposition
Chicago, IL
» Visit the website |
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16–18 September 2013
Applied Pharmaceutical Analysis
Boston, MA
» Visit the website |
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20 September–4 October 2013
SciX 2013 - The Great SCIentific eXchange
Milwaukee, WI USA
» Visit the website |
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23–25 September 2013
Polyurethanes 2013
Phoenix, AZ
» Visit the website |
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23–26 September 2013
10th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry
Boston, MA
» Visit the website |
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24–26 September 2013
Analitica South America
Sao Paulo, SP., Brazil
» Visit the website |
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24–26 September 2013
Analytica China
Shanghai, China
» Visit the website |
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25–28 September 2013
New Achievements in Chromatography – 19th International Symposium on Separation Sciences
Porec, Croatia
» Visit the website |
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6–9 October 2013
20th International Symposium on Electro- and Liquid- Phase-Separation Techniques(ITP2013)
Puerto de la Cruz, Tenerife, Canary Islands (Spain)
» Visit the website |
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