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The LCGC Blog
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The Dimensionality of Separations: Mass Spectrometry Is Separation Science
In many cases, multidimensional chromatographic separations are interfaced with mass spectrometry (MS) detection to obtain high sensitivity and specificity. Then why is MS typically not considered as just another separation dimension? Kevin Schug discusses the power of MS for resolving an enormous number of compounds in a sample. More...
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Special Maintenance Savings
You already know that an instrument failures waste time, sample, effort and money. However, did you know that 60% of instrument failures are caused not by instrument malfunction, but by a lack of preventive maintenance? Don’t risk your lab’s productivity. Get factory recommended maintenance for your Agilent systems  request a PM or PM/OQ quote and enjoy special limited time savings. |
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| Featured News |
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Non-invasive Test Uses GC–MS to Diagnose Pancreatic Cancer
A team of researchers from the Kobe University Graduate School of Medicine in Japan have developed a metabolomics-based approach to diagnose early-stage pancreatic cancer. More... |
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Get better MS results when working with low analyte concentrations
White Paper explains the technology behind Waters TruView™ LCMS Certified Vials–specially manufactured to minimize adsorption. These are the only vials tested and certified for analyte recovery by UPLC®/MS/MS, making them the most reliable sample vials available.
 Download White Paper |
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Strong Support for HPLC and LC–MS Training Courses in China
Training courses in the practical applications of high-performance liquid chromatography (HPLC) and liquid chromatography–mass spectrometry (LC–MS) were held in Hangzhou on April 12, 2013. More... |
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Essential Designer Drug Reference Kit
In order to facilitate rapid screening and identification of designer drug compounds, Agilent has expanded its Application Compendiums to include designer stimulants and cannabinoid compounds such as “bath salts.” The updated compendium and library also contain information regarding GC/QQQ and GC/Ion Trap analysis of these designer drugs.
 Request your copy. |
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Survey:
If you are you planning to attend HPLC2013 Amsterdam what is your main reason?
Click here to participate |
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CHROMacademy Workshop: Understanding Practical HPLC
Join us June 10th & 11th in Princeton, NJ for a revolutionary approach to learning about HPLC. We have eliminated the traditional (and boring) approach to teaching HPLC, and created an exciting new way to learn about one of the most powerful techniques in the analytical laboratory.  Register Now |
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| LC Troubleshooting
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Need Help With LC Troubleshooting?
A free interactive LC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It's completely free.  More. |
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5 Years Free Access to CHROMacademy
To show our commitment to learning, we have decided to offer all university students and staff free access to CHROMacademy. You are the future leaders and innovators of the scientific community, and by offering free access to CHROMacademy we hope to help you realize your potential. This has been made possible by Agilent Technologies- the world’s premiere measurement company.  Learn more |
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| Application Note |
Retain Hydrophobic & Hydrophilic Compounds in a "HILIC like" mode
J.E. Young, J.J. Pesek, and M.T. Matyska, MicroSolv Technology Corporation
One of the advantages of aqueous normal phase (ANP) chromatography is that both hydrophobic and hydrophilic compounds can be retained and this note shows an example. Although cyclobenzaprine has a log P of approximately 4.6–4.9, it is retained with a symmetrical peak shape.
Read More |
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| Featured Product |
Samplicity® Filtration System
The Samplicity® system provides a higher throughput, ergonomic alternative to syringe-tip filters for the preparation of liquid chromatography samples. The vacuum-driven system enables simultaneous filtration of up to 8 samples in seconds, including hard-to-filter samples.  Learn more
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Rugged C18 Increases Productivity
New Hamilton PRP-C18 HPLC Column provides high-efficiency reversed-phase separations over an extended column life in nearly any mobile phase at any pH.  Learn more
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Viscotek TDAmax for GPC/SEC
The Viscotek TDAmax sets the standard in advanced GPC/SEC systems. It is a complete solution, suitable for all macromolecular applications, incorporating high sensitivity refractive index, viscometer, and light scattering detectors. Learn more
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TSKgel STAT Columns
TSKgel STAT ion exchange non-porous resin columns, including TSKgel Q-STAT, TSKgel DNA-STAT, TSKgel CM-STAT, and TSKgel SP-STAT, contain large particles (5, 7 and 10 μm). This relatively large particle size, combined with an innovative bonding chemistry, results in columns that enable fast equilibration and analysis of complex biomolecular samples, such as proteins, peptides, DNA fragments, nucleic acids, and nucleotides.
 Visit our website to learn more about how TSKgel STAT columns can help your applications surpass the status quo today!
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Vials
L-MARK Absolute vials from LEAP Pal Parts & Consumables are manufactured with a process that reportedly minimizes the free hydroxyl sites on the glass surface. According to the company, the vials allow measurements to be made with minimal effects of sample absorption and pH shifts, increasing the accuracy of the analysis. LEAP Pal Parts & Consumables LLC, Raleigh, NC.
 www.palparts.com
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| New Webcasts |
Editors' Series: Faster Gas Chromatography in Practice
Wednesday, May 22, 2013
11:00 AM EDT.
Want faster GC separations? Tune in to learn a convenient method for selecting the most appropriate route for speeding up specific GC applications.
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Solving One of Chromatography’s Biggest Dilemma — Proper Sealing of Chromatography Autosamper Vials — Using the Advanced Vial Closure System (AVCS)
Thursday, June 6, 2013
8:00 am PDT/ 11:00 am EDT/ 16:00 BST/ 17:00 CEDT.
This web seminar will review the impact an innovative vial & closure design, like AVCS, can have on improving data quality by providing data that supports how an AVCS-designed vial & closure eliminates under and over compression of vial seals while improving robotic autosampler pick-up of vials, ensuring more centered vial closure positioning and greater optical recognition of vials placed in autosamplers. |
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Tips and Tricks on Screening and Confirmatory Methods for Residues and Contaminants in Foods
Tuesday, June18, 2013
11:00 AM EDT.
Tips and Tricks on Screening and Confirmatory Methods for Residues and Contaminants in Foods. |
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Editors’ Series: A Generic HPLC-UV Platform Method for Cleaning Verification
Wednesday, June 26, 2013
11:00 AM EDT.
Tune in to learn about the development and qualification of a simple, 10-min generic HPLC-UV gradient method for quantitative assays used in cleaning verification in a pharmaceutical environment.
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| Upcoming Events |
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12-16 May 2013
37th International Symposium on Capillary Chromatography and 10th GCxGC Symposium
Palm Springs, CA
» Visit the website |
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15-17 May 2013
The 44th ACS Central Regional Meeting
Mount Pleasant, MI
» Visit the website |
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16 May 2013
30th Triangle Chromatography Symposium
Raleigh, NCL
» Visit the website |
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19-24 May 2013
FOA 2013, International Symposium on Fundamentals of Adsorption
Baltimore, MD
» Visit the website |
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22–24 May 2013
FSEA Annual Spring Meeting and Technical Session
Clearwater Beach, FL
» Visit the website |
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6–7 June 2013
European Lab Automation 2013
Hamburg, Germany
» Visit the website |
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9–13 June 2013
61st ASMS Conference on Mass Spectrometry and Allied Topics
Minneapolis, MN
» Visit the website |
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16–20 June 2013
HPLC 2013: 39th International Symposium on High-Performance Liquid-Phase Separations and Related Techniques
Amsterdam, The Netherlands
» Visit the website |
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18–20 June 2013
Green Chemistry & Engineering Conference (GC&E)
Bethesda, MD
» Visit the website |
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19–20 June 2013
Lab Trends Conference
Atlantic City, NJ
» Visit the website |
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25–28 June 2013
Air & Waste Management Association 106th Annual Conference
Chicago, IL
» Visit the website |
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30 June–3 July 2013
24th International Symposium on Pharmaceutical and Biomedical Analysis
Reims, France
» Visit the website |
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2–5 July 2013
In Vino Analytica Scientia
Bologna, Italy
» Visit the website |
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4–17 July 2013
PREP 2013 — 26th International Symposium
Boston, MA
» Visit the website |
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7–12 July 2013
Chirality 2013
Shanghai, China
» Visit the website |
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