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February 26, 2013
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Chromatography News

Thin Layer Chromatography Detects Sub-standard TB Drug
In a random study of drugs from 713 pharmacies from 19 countries, 9.1% of anti-tuberculosis drugs analysed failed basic quality control (QC) testing using thin layer chromatography (TLC) for the required level of active pharmaceutical ingredient (API), according to a recent study published in the International Journal of Tuberculosis and Lung Disease.1
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HPLC Analysis Shows Vitamin D Supplement Potency Varies
The amount of vitamin D in supplements can range from 9% to 146% of the stated dose, according to a research letter published in the JAMA Internal Medicine.
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Essential to the development of biotherapeutics is ability to quickly and accurately assess product quality—including factors such as sequence integrity, glycan heterogeneity, and purity—at each step. Thermo Scientific workflows for intact-protein analysis enable these assessments early in the development process without the effort of complete characterization and allowing you to make better, faster decisions about how to proceed with your biotherapeutic development. Learn More.
 
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Capillary Electrophoresis–Mass Spectrometry for the Analysis of Biopharmaceuticals
CE–TOF-MS may provide a promising means for the qualitative and quantitative assessment of the heterogeneity of (glycosylated) biopharmaceutical products.
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