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| The LCGC Blog |
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The LCGC Blog: Chromatography Technical Tips - Polar Analyte Retention and Phase Collapse
Why would one want to use a mobile phase containing 100% water? Usually to wash the analyte or old mobile phase from the column (stationary phase surface) or to help retain analytes which elute quickly using mobile phases containing only very small amounts of organic solvent (usually highly polar analytes). More...
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Automated SPE of Base, Neutral and Acid Semi Volatiles in Industrial Waste Water
Traditional ABN extractions are time consuming and often result in poor results. By incorporating FMS TurboTrace® ABN system these samples can be extracted with a single pass procedure without emulsions, centrifuging and hours of manual labor. The system is designed to handle multiple cartridges, and is a fully automated solution. View the recorded webinar.  Learn More |
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| Featured Video |
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LCGC TV: Screening Environmental Pollutants in Water Samples
Anthony Gravell of Natural Resources Wales describes a recent study comparing passive sampling with spot sampling to determine pollutants (including PAHs) in drinking water zones in England and Wales. More...
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More Efficiency, More Free Time
All you expect, and more. The new Agilent 1290 Infinity II LC sets new benchmarks in analytical, instrument and laboratory efficiency. You may find yourself with extra time on your hands.
Meet the next generation of Agilent UHPLC:
 http://EfficientUHPLC.agilent.com
#EfficientUHPLC |
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| Featured Article |
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How Much Can I Inject? Part I: Injecting in Mobile Phase
At first glance, injection of sample onto a liquid chromatography (LC) column seems pretty simple — just put the sample in a vial, select the desired injection volume in the autosampler settings, and push the start button. However, before starting an LC method, we should check a few variables to be sure that we are not creating a potential problem. More... |
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New purity method increases productivity - Join the conversation
Traditional method development, in which an LC method is developed principally by trial-and-error, is time consuming and may not result in a robust method. Plus, it provides no understanding of the influence of key factors on the results. Learn about a unique approach in the development of a new purity method for a well-known API that, with an analysis time of only 4 minutes, provides a 40-fold increase in productivity.
 Register Today. |
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When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration
The top five adulterated foods, the latest contaminants found in them, and the methods to detect those compounds. More... |
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Antibody Drug Conjugate (ADC) Characterization
New RPC, HIC, IEX and SEC columns for analyzing antibody drug conjugates, include an advanced RPC polymer chemistry, PolyRP™-1000Å, available from The Nest Group, Inc.. For non-denaturing analyses, Zenix™ SEC, PolyPROPYL A™ HIC, and PolyCAT A® WCX columns separate aggregates, deamidation products or oxidized forms of your antibody.  Try one of our ADC characterization approaches today! The Nest Group, Inc. - "Not Just Columns ... Answers!" |
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Electronic Control of Carrier Gas Pressure, Flow, and Velocity
Have you wondered how your gas chromatography (GC) system sets and controls gas pressures, flows, and carrier gas velocities electronically? Here, we describe requirements for and the operation of electronic gas control systems for GC columns and detectors. More... |
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HPLC Columns & Bulk Packings
SMT HPLC columns are available in various phases of carbon loads for optimal selectivity. Our popular O (C8) and OD (C18) columns are known to tolerate aggressive pH conditions [1-12] and are stable at extended temperatures [25°C to 90°C]. SMT also offers specialty columns and bulk packings for unique applications.  Try our columns and/or bulk packings today! Separation Methods Technologies, Inc. - "Providing separation alternatives!” |
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| GC Troubleshooting |
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Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. More... |
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Six Degrees of Separations to Product Savings from VWR®
The products you’re using, the products you'll need, from the suppliers you trust – that’s the VWR® Chromatography Advantage. At VWR®, you will find an extensive selection of products and services for a variety of chromatography techniques and applications to support your demanding requirements.  Visit vwr.com today for our latest 'Six Degrees of Separations' product promotions and enter to win a heat-sensitive, color changing coffee mug. |
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| Featured Products |
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EconoTrace® SPE System
An economical solution for consistent, reproducible, high throughput extractions for pharmaceutical, food and water matrices. Up to 8 extractions can run simultaneously. The system uses any SPE cartridge size or type.  Learn More
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Protein SEC made simple
Malvern’s OmniSEC GPC/SEC software now has selectable "polymers" or "proteins" user interfaces, simplified workflows and integration with Waters Empower® for improved productivity. Adding the Viscotek SEC-MALS 20 detector to your SEC system is even easier!  Learn More
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| On Demand Webcasts |
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| Online Sample Cleanup — A Cost-Efficient Alternative to Conventional SPE and Liquid–Liquid Extraction Methods Thermo Fisher Scientific |
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| Analytical Separation of Antibody Drug Conjugates (ADCs) and Monoclonal Antibodies (mAbs) Various Chromatographic Modes |
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| Next Generation UHPLC Technologies: Change the Landscape in LC |
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| Automated Solid Phase Extraction for the Environmental Testing Laboratory |
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| Development and Applications of Liquid Chromatography-High Resolution Mass Spectrometry for the Analysis of Chemical Contaminants in Foods |
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| Utilizing PepFinder Software for Interrogation of LC-MS Peptide Map Data of Biotherapeutics |
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| New Webcasts |
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Add Isotope Ratio Information to Your Research
Wednesday, October 22, 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST |
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In situ Moisture Analysis of Lyophilized Products
Wednesday, October 29 , 2014 8:00 AM PDT/ 10:00 AM CDT/ 11:00 AM EDT |
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Editors’ Series: Quality Control of Dietary Supplements: An Examination of Chromatographic Approaches Needed for cGMP Compliance, with Case Studies
Wednesday, November 5, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET |
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Future-proofing Your GC-MS Analysis: Triple Quad Workflows on Demand
Thursday, November 6, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET |
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Editors’ Series: The Use of Silica Hydride-Based Stationary Phase for the HPLC Analysis of Food and Beverage Products
Tuesday, November 11, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET |
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Fast and Accurate Analysis of Beer and Wort Samples Using Automated Discrete Analysis
Thursday, December 11, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET |
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| Upcoming Events |
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November 5–7
30th Montreux LC/MS Symposium
Charleston, SC
» Visit the website |
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November 17–19
Eastern Analytical Symposium and Exposition (EAS)
Somerset, NJ
» Visit the website |
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