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June 14, 2012
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Chromatography Corner

Challenging Beliefs About How Core–Shell Particles Work
In a new paper to be published in the July issue of LCGC North America, Fabrice Gritti and Georges Guiochon of the Department of Chemistry at the University of Tennessee (Knoxville, Tennessee) present results from their latest studies in their research on the kinetic mechanisms of chromatography columns packed with core–shell particles.
New Podcast Series: The 2012 FACSS-SciX Awards

Tracking Molecular Transport in Chromatographic Particles with Single-Molecule Fluorescence Imaging
Justin Cooper and Joel Harris at the University of Utah are using single-molecule fluorescence imaging to study the dynamics of molecular transport within chromatographic stationary phases. Here is what they have found.
How to remove more than 95% of phospholipids from plasma and serum
Ostro 96-well plate is a simple solution for the cleanup of plasma samples that allows more sensitive analyses, increases sample throughput, reduces instrument downtime, and increases productivity. Requiring minimal to no method development, this technology can be quickly implement into your laboratory's workflow. Download the latest Ostro application notes.
Featured News

ChromaDex and the Scripps Research Institute Collaborate
ChromaDex Corporation (CDXC) (Irvine, California, USA) has announced that it has collaborated with the Scripps Center for Metabolomics (La Jolla, California) to generate tandem mass spectrometry data for compounds from the ChromaDex natural products and phytochemical catalog.
Power up Your Flexibility: Experience a new level in quaternary pump performance
The new Agilent 1290 Infinity Quaternary Pump is the only low-pressure mixing UHPLC pump offering the accuracy and precision of a high-pressure mixing binary pump. This unique combination enables the most accurate and reliable analysis, combined with the flexibility of ternary and quaternary gradients, precise buffer blending, and method development capability.
FSA Ends Animal Testing in Shellfish Program
The Food Standards Agency (FSA) (London, UK) has announced that it has ended the practice of using mice for the detection of paralytic shellfish poisoning (PSP) and lipophilic toxins in commercially harvested shellfish.
VICI's New Catalog
VICI Valco Instruments Co Inc introduces its new general catalog #65. The VICI catalog has been called “the bible of chromatography”. Its first catalog since 2009, the VICI family presents the latest product developments as well as the full line of Valco and Cheminert® GC, LC, HPLC, and UHPLC valves, fittings, and accessories, as well as Metronics calibration devices and Precision Sampling products. There is even a glossary and handy reference section. Ask for yours today
KineMed and CHDI Collaboration
KineMed Inc., (Emeryville, California) and CHDI Foundation (New York, New York) have entered into a collaboration that will see KineMed's isotopic labeling and dynamic proteomics platform be used to investigate the turnover rates of huntingtin protein.
Thermo Scientific is now sponsoring CHROMacademy's HPLC Troubleshooter, the only tool available in which multiple symptoms can be combined to form a true representation of the problem. Read more.
Featured Products

Tosoh Technical Seminar at HPLC
Visit Tosoh Bioscience in booth #327 at HPLC 2012 in Anaheim. Tuesday afternoon, our Technical Service Manager, Atis Chakrabarti, Ph.D., will be presenting the seminar "Detection of Protein Heterogeneity by HPLC using different modes of chromatography including the new novel SEC and RPC columns from Tosoh." Click here for the full abstract and to reserve your seat.
Recent discussions on CHROMmunity, a Forum and Networking Site for Chromatographers
LC-ESI-MS of Methane Sulfonamide
Join in the conversation. Free Registration.>>
Upcoming Webcasts

The CHROMacademy Guide To Troubleshooting GC Separations
Thursday, June 14, 2012
11:00 AM EDT; 16:00 GMT
The Essential Guide from LCGCs CHROMacademy presents the third in our series of webcasts on Practical GC Troubleshooting. In this session, Dr. John Hinshaw (Senior Scientist , BPL Global Ltd) and Tony Taylor (Technical Director, Crawford Scientific), present practical troubleshooting tips for GC separations, with special emphasis on retention time variability, loss of efficiency and poor peak shape.
Mass Spectrometry Tool Box - Biopharmaceutical Characterization
Wednesday, June 20, 2012
11:00A AM EDT
To achieve a greater understanding of your biotherapeutic product and to satisfy the stringent requirements of the regulators, characterization strategies need to be employed throughout biopharmaceutical discovery, development, regulatory approval and production. Mass spectrometric tools can help provide you with the necessary characterization knowledge quickly and confidently.
EDITORS' SERIES: A Roadmap for Rapid HPLC Method Development: A Practical Three-Pronged Approach
Tuesday, June 26, 2012
11:00 AM EDT
HPLC method development is a challenging task, requiring the ability to optimize a large number of dependent and independent variables for complex samples. The traditional method development approach, while well accepted, is difficult to implement in practice, particularly for those with little experience. In this seminar, we describe the concept of a practical, three-pronged approach for rapid method development.
Upcoming Events

16–21 June
37th International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC 2012)
Anaheim, CA
» Visit the website
18–21 June
BIO International Convention
Boston, MA
» Visit the website
15–18 July
PREP 2012 International Symposium on Preparative and Process Chromatography
Boston, MA
» Visit the website
12–17 August
XXI International Materials Research Congress (IMRC) 2012
Cancun, Mexico
» Visit the website
9–13 September
29th International Symposium on Chromatography (ISC)
Torun, Poland
» Visit the website
11–14 September
9th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry (Mass Spec 2012)
San Diego, CA
» Visit the website
30 September–3 October
International Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA 2012)
Brussels, Belgium
» Visit the website
30 September–4 October
CE in the Biotechnology & Pharmaceutical Industries: 14th Symposium on the Practical Applications for the Analysis of Proteins, Nucleotides, and Small Molecules
Scottsdale, AZ
» Visit the website
21–24 October
4th International Conference on Polyolefin Characterization
Houston, TX
» Visit the website
25–30 November
Materials Research Society (MRS) Fall Meeting & Exhibition
Boston, MA
» Visit the website