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May 15, 2014
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The LCGC Blog

The LCGC Blog: GC Inlet Maintenance...Have You Really Heard It All Before?
Many troubleshooting investigations in chromatography often don't lead to a single causal factor. Often, the reason for problems or lack of method robustness are related to many small "contributory factors" and this is particularly true of the problems associated with sample introduction in capillary gas chromatography.  More...
Webinar “The Analysis of Perfluoroalkyl Contaminants in Samples Obtained from the Great Lakes”
Speakers: Thomas M. Holson Professor, Bernard S. Crimmins,  Associate Professor, at the Center for Air Resources Engineering and Science, Clarkson University will discuss the analysis of PFCs in Water and the Food Chain. Join FMS, Inc. to learn more Register for the webinar June 4th, 2014 11:00 am EST.
Featured Interview

What's Behind the Trends in Sample Preparation?
There are some interesting shifts going on in sample preparation. In this new short video interview, Doug Raynie of South Dakota State University discusses what is behind the trends — starting with the fundamental differences in strategies for solid and liquid samples.  More...
Fast Little Column for MAbs
Agilent Bio-Monolith Protein A columns enable fast, accurate MAb titer analysis over a wide concentration range with minimal plugging from cell debris. Don’t be put-off by the funny shape; you’ll be surprised what this fast little column can do.Get application note and request free trial.
Featured Article

Metabolomics in Food and Nutrition Laboratories
The potential to accurately and rapidly measure hundreds of individual molecular species provides novel opportunities for food and nutrition sciences. By enabling the molecular fingerprinting of food components and their metabolites, metabolomics is helping scientists to investigate the intricate relationship between food and human health. Here, we look at the various applications, strategies, and tools related to metabolomics.  More...
Solutions to Your Challenges in Gas Chromatography
We all know that chromatography is full of complexity. The Chromatography Solutions Center is here to help. The Solution Center, developed by LCGC in coordination with Thermo Scientific, can help you find answers to your analytical challenges by providing a variety of articles, application notes, videos, and other resources - updated monthly.Check out this month's installment of the Gas Chromatography section.
GC Troubleshooting

Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In three simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. More...
Introducing: Lab Water Solution Center
The Lab Water Solution Center, developed by LCGC in coordination with EMD Millipore, can help you process and manage your lab water solutions by providing a variety of articles, webinars, videos, and other resources on lab water — updated monthly.Visit to find these resources and more.
Featured Products

Millitrack® e-Solutions
Millitrack® e-Solutions software for water purification systems ensures optimal daily performance with continuous quality improvement.  This unique software allows easy remote monitoring and diagnostics, in order to minimize system downtime and increase productivity.
Learn more
Compound Searchsm by Wiley
Compound Search is a free service enabling researchers to verify compound coverage in databases and spectral libraries published by Wiley and Wiley-VCH.  Compound Search enables users to perform text searches (name, synonym, InChI, InChI key, mass, formula) and structure searches.
Learn more
Enduris UHPLC Seal
The Enduris UHPLC Seal is the first seal proven to deliver consistent, long-term performance in liquid chromatography pumps at pressures of 22,000 PSI and higher, increasing LC throughput and sample resolution while reducing equipment downtime.
Learn more
New Webcasts

Clinical Applications of LC-MS:  Development and Research Application of a Highly Sensitive LC-MS Method for Quantification of a Cholesterol Protein in Plasma
Thursday, May 15 , 2014, 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
This webinar will discuss this method, from method development (optimal antibody determination using MSIA and SRM LC–MS-MS in terms of PTM determination, LOD/LOQ, and linearity over PCSK9’s clinical dynamic range) to applying to a test case with control plasma samples and samples with a known mutation to determine method specificity. In summary, a robust and sensitive MSIA-SRM method was developed for the absolute quantification of all PCSK9 domains and a PTM in plasma.
Complete Inorganic Elemental Speciation Analysis Solutions for Food Safety
Tuesday, May 20, 2014, 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
The food safety industries have significantly increased their interest in understanding an element’s various chemical forms due to pending legislative pressures. This webcast will provide insight into the latest developments in speciation technology and offer proof data for a wide variety of applications, including arsenic species in apple juice and rice syrup and iodine species in milk.
Part Three: Editors’ Series: Analysis and Identification of Emerging Contaminants and their Transformation Products in River Water, Urban Water, and Hospital Wastewaters: Sample Preparation and LC-MS Techniques
Wednesday, May 21, 2014, 8:00 AM PDT/ 10:00 AM EDT/ 11:00 AM EDT
Tune in to learn about advanced methods — with special emphasis on green methods —for sample preparation, GC–MS, GC with comprehensive MS, and LC–MS for contaminants including current and emerging disinfection byproducts, odorous compounds and precursors, hormones and pharmaceuticals, and pesticides and their byproducts.
Features of Different Mass Analysers Applied to Multi-Allergen Screening
Wednesday, May 28, 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
In this webinar, a comparison of two mass spectrometry-based approaches for multiplex detection of residual allergens in food matrices will be presented.
Suitability of Ionic Liquid GC Columns for Various Applications
Thursday, June 12, 2014, 8:00 AM PDT/ 10:00 AM CDT/ 11:00 AM EDT
Discover the features and benefits of ionic liquid GC columns: More interaction mechanisms, to provide selectivity options; no hydroxyls, reducing damage from moisture and oxygen; extended polarity, for increased orthogonality.
The Application of Enhanced Detection and Confirmation Criteria in Forensic Toxicology Screening Using an Accurate Mass UHPLC-QTOF System
Friday, June 13 , 2014 8:00 am PDT/ 10:00 AM CDT/ 11:00 AM EDT
This webinar will demonstrate the challenges and solutions that are being employed in forensic toxicology to rapidly screen for illicit drugs (including designer drugs), poisons, and their metabolites in human body fluids. You will learn about a new workflow to overcome these challenges.
From TLC to Flash to Prep-HPLC on BUCHI’s New All-In-One Solution – PrepChrom C-700
Wednesday, June 18, 2014 8:00 AM PDT/ 10:00 AM CDT/ 11:00 AM EDT
What if there were a way to combine flash chromatography and preparative HPLC into one solution that took up a quarter of the space? Learn about how you can go from TLC to purified product without multiple instruments and without being an expert in chromatography.
Upcoming Events

18–23 May 2014
38th International Symposium On Capillary Chromatography and the 11th GCxGC Symposium
Riva del Garda, Italy
» Visit the website
25–28 May 2014
ExTech 2014
Chania, Crete, Greece
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11–12 June 2014
Bio/Pharmaceutical and Medical Device Product Recalls Summit
San Diego, CA
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17–18 June 2014
Validation Week Puerto Rico
San Juan, PR
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20–23 July 2014
PREP 2014 Symposium on Preparative and Process Chromatography
Boston, MA
» Visit the website
31 August–5 September 2014
Dioxin Madrid 2014: 34th International Symposium on Halogenated Persistent Organic Compounds
Madrid, Spain
» Visit the website
14–18 September 2014
ISC 2014 – Salzburg Austria, 30th International Symposium on Chromatography
Salzburg, Austria
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5–8 October 2014
15th International Symposium on Preparative and Industrial Chromatography and Allied Techniques, SPICA 2014
Base, Switzerland
» Visit the website
14–15 October 2014
Gulf Coast October Conference
Galviston, TX
» Visit the website