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April 10, 2014
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The LCGC Blog

My Own March Madness — Four Dissertations, Analytical Chemistry, and Chemical Education
With four graduate students completing their doctoral dissertations at the same time has created a sort of "analytical chemistry March madness" for professor and blogger Kevin Schug. And the research of these "final four" is certainly worth watching.  More...
Chromolith® High Resolution Column
Revolutionary monolithic silica columns are a single rod of high purity monolithic silica instead of particles. A unique bimodal pore structure gives greatly improved chromatographic performance. This leads mainly to improved separation efficiency and column back-pressure and allows for faster flow rates, considerably reducing the analysis time while enhancing the lifetime. Learn more
Featured Interview
Two-Dimensional LC in Pharmaceutical Analysis: Advantages and Challenges
Two-dimensional liquid chromatography has moved from academia into industry. In two new short video interviews, Kelly Zhang of Genentech talks about the advantages gained by developing a two-dimensional LC method for analyzing impurities in pharmaceuticals, as well as the challenges in developing the method.  More...
Application Note
Analysis of Intact Human Insulin and 5 Analogs in Human Plasma
This work provides a single, simple method for the simultaneous, direct quantification of intact human insulin and multiple insulin analogs in human plasma, achieving LODs of 50 to 200 pg/mL for each. This study takes advantage of mixed-mode solid-phase extraction (SPE) and a high-efficiency, solid-core particle column that contains a low-level positive surface charge to eliminate interferences while facilitating high sensitivity quantification. More...
Solutions to Your Challenges in Ion Chromatography
We all know that chromatography is full of complexity. The Chromatography Solution Center is here to help. Check out this month’s installment of the Ion Chromatography section, featuring Practical and Popular Sample Prep Techniques for IC, Speciation Applications Summary IC, IC webinar, application note, white paper, and more. Learn more
Featured Article
LC Method Scaling, Part II: Gradient Separations
AIf scaling isocratic separations is so simple, why is gradient scaling so confusing? In this installation of LC Troubleshooting, columnist John Dolan offers advice on the proper scaling of gradient methods.  More...
Waters introduces the ACQUITY QDa Detector
The future is now separated from the past.  Imagine a lab where all analytical scientists can acquire high-quality mass spectral data. On their own. Within their existing workflows. Across every sample. Without training. Waters imagined just that and introduces the ACQUITY QDa Detector. Click Here
GC Troubleshooting

Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In three simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. More...
Featured Products
The First SEC-MALS detector for UHPLC
The mDAWN™ is the world’s first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins.
Learn more
TurboTrace ABN Solid Phase Extraction System
The TurboTrace ABN SPE system combines Dual Cartridge extraction, fractionation, drying and concentration automating the entire process from start to finish for Base, Neutral and Acid, Semi-Volatiles in Water.
Learn more
New Webcasts

Editors’ Series: Water Analysis:  Emerging Environmental Contaminants and Current Issues
Wednesday, April 23, 2014 8:00am PDT/ 11:00 AM EDT
Tune in to hear Susan Richardson, formerly of the US Environmental Protection Agency and now at the University of South Carolina, to learn about emerging contaminants in our water systems and advances in analytical methods to detect and monitor them.
The Analysis of Dioxins in Food with a High Performance GC-Triple Quadrupole System According to EU 252/2012 Regulations
Wednesday, April 29, 2014 8:00am PDT/ 10:00 am CDT/ 11:00 AM EDT
This webinar will demonstrate the challenges and solutions of analysis of dioxins in food matrices.  You will learn new methods to overcome analysis challenges.
Making Better GC Connections While Ensuring an Inert Sample Flow Path
Thursday, April 30, 2014 10:00 am PDT/ 12:00 PM CDT/ 1:00PM EDT
Explore and learn about quick and easy ways to simplify column installation and the productivity gains you can achieve through improved column connections and flow path inertness offerings, which include:  new inert retention gaps and guard columns, new column connectors, and ferrules.
Editors’ Series: Investigating the Potential Impact of Hydraulic Fracturing on Private Well Water Quality
Thursday, May 8, 2014 8:00 am PDT/ 10:00 AM CDT/ 11:00 AM EDT
Until now, limited studies have been performed regarding the environmental impact of hydraulic fracturing for harvesting natural gas. In this seminar, Kevin Schug discusses the suite of analytical methods (including headspace-GC, GC-MS, ICP-OES, ICP-MS, total organic carbon, and ion chromatography methods) his team developed to evaluate the quality of private well water in proximity to natural gas extraction sites. This talk will report on the results of their studies to date, future plans, and the opportunity presented by his baseline studies of future fracking sites.
Upcoming Events

11–15 May 2014
HPLC 2014
New Orleans, LA
» Visit the website
18–23 May 2014
38th International Symposium On Capillary Chromatography and the 11th GCxGC Symposium
Riva del Garda, Italy
» Visit the website
25–28 May 2014
ExTech 2014
Chania, Crete, Greece
» Visit the website
20–23 July 2014
PREP 2014 Symposium on Preparative and Process Chromatography
Boston, MA
» Visit the website
20 August–5 September 2014
Dioxin Madrid 2014: 34th International Symposium on Halogenated Persistent Organic Compounds
Madrid, Spain
» Visit the website
14–18 September 2014
ISC 2014 – Salzburg Austria, 30th International Symposium on Chromatography
Salzburg, Austria
» Visit the website