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Chromatography Corner |
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Emerging Trends in Pharmaceutical Analysis
Benedetto Natalini, Director of the Department of Pharmaceutical Sciences, at the University of Perugia in Italy spoke to LCGC about the driving forces in pharmaceutical analysis, including the importance of regulation, chirality, and miniaturization. Natalini also discussed his recent research in chiral chromatography, as well as developments in diagnostics using novel orthogonal liquid chromatography methods to quantify neurotransmitters involved in Parkinson’s disease.
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CDS Helps Customers Comply with 21 CFR Part 11
Learn how a GMP-compliant, CMO with full data audit trails, networked solution and centralized data storage are seeing 30% savings in lab bench space and significant productivity increases. Sigma-Aldrich uses Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System software to control more than 45 LC and GC systems between multiple departments, ensuring data integrity trails and a networked.  Learn more |
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Analysis of Complex Pharmaceuticals by Ultrahigh-Pressure Liquid Chromatography: Case Studies and Quality Control Implications
In this article, we present experimental results and method validation data from two analytical case studies of complex small-molecule pharmaceuticals to illustrate the utility and potential advantages of ultrahigh-pressure liquid chromatography (UHPLC) in high-resolution separations, particularly for quality control purposes. The focus is on the use of UHPLC in potency assays and purity analysis of complex drug substances and drug products using UV detection, where resolution of all analytes is required. Finally, we discuss some potential technical issues and mitigation strategies for conducting these high-resolution chromatographic analyses in a regulated environment.
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Featured Product |
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LCMS Biopharma Application Compendium
Description: View this interactive collection of application notes and peer reviewed publications to learn more about current biopharma applications.  Learn more
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| Chromatography & Mass Spectrometry Solution Centers |
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Resources for Pharma Analysis
We all know that pharmaceutical analysis is full of complexity. The Chromatography Solution Center, developed by LCGC in coordination with a leading supplier, can help — by providing a variety of articles, application notes, videos, and other resources — updated monthly. This month's offering includes:
Mass Spectrometry Solution Center &
Chromatography Solution Center
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LC Troubleshooting |
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Need Help With LC Troubleshooting?
A free interactive LC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It's completely free.
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| On Demand Webcasts |
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New Innovations in UHPLC and LCMS Workflows for the Comprehensive Characterization of Monoclonal Antibodies [mAbs] and Antibody Drug Conjugates [ADCs]
Editors’ Series: The Use of Silica Hydride-Based Stationary Phase for the HPLC Analysis of Food and Beverage Products
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| Upcoming Events |
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January 26–27 2015
3rd Stir Bar Sorptive Extraction Technical Meeting
Paris, France
» Visit the website |
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February 7–11, 2015
SLAS 2015
Washington DC, USA
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April 15–17, 2015
Vietnam Analytica 2015
Ho Chi Minh City, Vietnam
» Visit the website |
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| New Webcasts |
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Streamline Data Analysis of Tandem Mass Spectrometry for Inborn Errors of Metabolism Research
Wednesday, December 10, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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Fast and Accurate Analysis of Beer and Wort Samples Using Automated Discrete Analysis
Thursday, December 11, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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