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11 September 2014 |
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Image Credit: Ethan Myerson/Getty Images |
Top Story: Current Practices and Considerations for a Stability-Indicating Method in Pharmaceutical Analysis
The demonstration of drug substance (DS) or drug product (DP) stability over the shelf life is a regulatory requirement in the pharmaceutical industry. To fulfill this requirement, a stability-indicating method (SIM) must be developed and validated to separate and quantify both the active pharmaceutical ingredient (API) and its related compounds (process impurities and degradation products). |
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| Fast, Reliable Glycan Mapping |
New Agilent AdvanceBio Glycan Mapping columns obtain high-resolution, reliable glycan maps in LESS THAN 10 MINUTES with 1.8 µm particles. 2.7 µm particles offer high resolution with lower backpressure, 1.8 µm for highest UHPLC resolution. Each batch of media is QA tested with a glycan sample to ensure consistent quality and robust performance. Glycan standards are available for performance testing and retention mapping.  Learn More |
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Photo credit: David Malan/Getty Images | LCGC Europe Supplement: Advances in Food Analysis
Food provides the body with energy, and good food is indispensable for a healthy life. With a worldwide population of over seven billion people, it is clear that state-of-the art technology is needed to provide food of a sufficient high quality. |
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| All You Expect, And More |
The next generation of Agilent UHPLC is coming.
See the launch at Analytica China, Shanghai, September 24 -26, 2014
#NextUHPLC
 http://NextUHPLC.agilent.com
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| Need GC Troubleshooting Help? |
The CHROMacademy interactive GC Troubleshooter, sponsored by Thermo Scientific, was designed with busy chromatographers in mind. In 3 simple steps ChromAcademy can help you overcome your instrument, separation and quantitation issues. It’s completely free — so if you haven't tried our troubleshooter before you're in for a surprise!  Learn More |
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Photo Credit: Pasika/Getty Images | News: Chiral Separation of I-MAMP and d-MAMP in Saliva
Scientists from the National Institute on Drug Abuse (Maryland, USA) and the University of Maryland Baltimore (Maryland, USA) have proposed precolumn derivatization using N(α)-(2,4-dinitro-5-fluorophenyl)-l-alaninamide (Marfey’s reagent) prior to LC–MS analysis for the quantitation of chiral amphetamines in plasma and saliva. |
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Photo Credit: kutay tanir/Getty Images | Entering the Second Dimension
Michael Frank, Senior Director of Global Marketing, Liquid Phase Separation Business at Agilent Technologies, talks about the rise of two-dimensional liquid chromatography (2D LC) and its potential for routine analysis. |
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Upcoming Webcasts
Utilizing PepFinder Software for Interrogation of LC–MS Peptide Map Data of Biotherapeutics
Thursday 17 September 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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Automated Solid-Phase Extraction for the Environmental Testing Laboratory
Wednesday 24 September 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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Pushing the Limits of Chromatography with Next Generation UHPLC Technologies: How Solid Core Column and Advanced UHPLC Technologies Change the Landscape in LC Labs
Thursday 25 September 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
Sign Up Now >>
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The First SEC-MALS detector for UHPLC |
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Shimadzu’s i -series integrated HPLC and UHPLC systems fit both small labs with limited space as well as large labs requiring high throughput operation. Providing high speed, outstanding performance, maintainability and economics, the i -series targets food, environmental, chemical and pharmaceutical industries.  Learn More |
The µDAWN™ is the world’s first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins.  Learn More |
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