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Pharmaceutical Sciences, Manufacturing & Marketplace Report October 23, 2013
  From Cynthia Challener, PhD, Editor, Pharmaceutical Sciences, Manufacturing & Marketplace Report
In this issue, the Parenteral Drug Association develops a science-based technical report to ensure effective use of blow-fill-seal technology. Waters develops a mass detector to overcome the barriers to adoption of mass spectrometry by analytical chemists, and GE Healthcare Life Sciences new advanced single-use bioreactor technology for easy and intelligent process control. Plus, advancing quality by design in small-molecule drug development and the latest on oral absorption enhancement strategies.		  
 

   
Stay current in the fast-paced world of biopharmaceutical and pharmaceutical development and manufacturing with a free subscription to the Pharmaceutical Sciences, Manufacturing & Marketplace Report.
 
Parenterals
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Maria Toutoudaki/Getty Images

Science-Based Technical Report Being Developed to Ensure Effective Use of Blow-Fill-Seal Technology

The Parenteral Drug Association has established a task force to develop a peer- and regulatory agency-reviewed Technical Report that will serve as a science-based industry reference document. Click Here to Read More

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Pharmaceutical Analysis
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Adam Gault/Getty Images
New Technology Enables Integrated Chromatographic Separation and Mass Detection

Mass detection at the push of a button could change the way many laboratories carry out their chromatographic analyses. Click Here to Read More
Join our Pharmaceutical Analysis Linked-In Community
 
Biological API Manufacturing
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Maciej Frolow/Getty Images
New Single-Use Bioreactor Technology Emphasizes Ease-of-Use and Intelligent Process Control

An updated bioreactor based on rocking technology has more advanced controls but is easier for biopharmaceutical manufacturers to use. Click Here to Read More
Join our Biological API Manufacturing Linked-In Community
 
Chemical API Manufacturing
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Alfred Pasieka/Getty Images

Quality by Design in APIs

The adoption of quality by design in small-molecule drug development and manufacturing continues to evolve as the industry seeks ways to augment process understanding for APIs. Click Here to Read More

Join our Chemical API Manufacturing Linked-In Community
 
Solid, Semisolid, and Specialty Dosage Forms
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Ion-Bogdan Dumitrescu/Getty Images

Evaluating Strategies for Oral Absorption Enhancement

Formulation scientists tackle the challenges of improving drug absorption across the gastrointestinal membrane. Click Here to Read More

Join our Solid, Semisolid, and Specialty Dosage Forms Linked-In Community
 
Other Recent Developments

GlaxoSmithKline, Novartis, and AstraZeneca Fund Center Focused on Advancing Commercial-Scale Continuous Crystallization
Through partnerships and collaborations between academia, industry, and the public sector, the Center for Continuous Manufacturing and Crystallization is advancing continuous crystallization technologies.

Sterile, Automated Sampling Enabling PAT for Biopharmaceutical Manufacturing
Pfizer, Eli Lilly, and several other pharmaceutical companies are participating in the development of automated sampling technology and associated software that improve process control and reduce development times in biopharmaceutical manufacturing.

On-Demand Drug Release Possible with Thermo-Responsive Polymers
On-demand drug release has the potential to reduce the side effects associated with the over-dosage of drugs, particularly for highly potent anti-cancer therapies.

Plasmon Resonance Microscopy Enables Analysis of Molecular-Scale Phenomena in Living Systems
Plasmonic imaging overcomes the limitations of traditional microscopy and can be used for the analysis of single cells, cell organelles, viruses, and even single protein-protein interactions.

Leveraging Singe-Use Learnings in Fill–Finish Operations
After realizing benefits from the adoption of a single-use filling line for one specific product, Patheon took the leap and installed a single-use filling line in a new facility.

 
The Pharmaceutical Sciences, Manufacturing & Marketplace Report is a biweekly newsletter of Pharmaceutical Technology and BioPharm International, and an exclusive feature of the new Pharmaceutical Technology/BioPharm International Marketplace, an online community focused on products and services for drug development and manufacturing. The Pharmaceutical Sciences, Manufacturing & Marketplace Report provides insight in five main communities: solid, semisolid, and specialty dosage forms; parenterals; chemical API manufacturing; biological API manufacturing; and pharmaceutical analysis.  
 
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Perspectives from Cynthia Challener, PhD, editor of the Pharmaceutical Sciences, Manufacturing & Marketplace Report and industry members
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