Marketplace eNewsletter Bi-Monthly | Having trouble viewing this e-mail? Click here.
Pharmaceutical Technology/BioPharm Marketplace eNewsletter

Pharmaceutical Sciences, Manufacturing & Marketplace Report August 14, 2013
  From Cynthia Challener, PhD, Editor, Pharmaceutical Sciences, Manufacturing & Marketplace Report
In this issue, researchers from Merck & Co. and the University of Pittsburgh discuss a rapid method for evaluation of residual palladium in pharma synthesis. Also, EMD Millipore and PharmaCell have advanced large-scale production of stem cells. Tetraphase Pharmaceuticals achieves the process-scale synthesis of a new tetracycline derivative. Plus approaches for screening for solid-state properties when formulating poorly soluble compounds and advances in extractables and leachables testing.		  
 

   
Stay current in the fast-paced world of biopharmaceutical and pharmaceutical development and manufacturing with a free subscription to the Pharmaceutical Sciences, Manufacturing & Marketplace Report.
 
Pharmaceutical Analysis
Image Placeholder
Maria Toutoudaki/Getty Images

Merck–PITT Collaboration Demonstrates Rapid Method for Evaluation of Residual Palladium

A simple, rapid analytical method for the determination of palladium in pharmaceutical production samples will speed up development and optimization of reactions involving palladium catalysts. Click Here to Read More

Join our Pharmaceutical Analysis Linked-In Community
Biological API Manufacturing
Image Placeholder
Maciej Frolow/Getty Images
Collaboration Formed to Develop Large-Scale Bioreactor Production of Stem Cells

EMD Millipore and PharmaCell have entered into a collaboration to develop optimized large-scale expansion and harvest of HepaRG cells using bioreactor technology. Click Here to Read More
Join our Biological API Manufacturing Linked-In Community
 
Chemical API Manufacturing
Image Placeholder
Alfred Pasieka/Getty Images
Tetraphase Pharmaceuticals Achieves Process-Scale Synthesis of New Tetracycline Derivative

Synthesis of tetracycline derivatives with novel substituents has been challenging. Using an approach based on a Michael−Dieckmann reaction, new compounds with enhanced antibiotic properties are now being prepared on a large scale. Click Here to Read More
Join our Chemical API Manufacturing Linked-In Community
 
Solid, Semisolid, and Specialty Dosage Forms
Image Placeholder
Ion-Bogdan Dumitrescu/Getty Images

Parallel Screening of Solid-State Characteristics Aids Formulation of Poorly Soluble Drugs

Rapid screening of critical API properties can quickly identify the best approach for increasing bioavailability.Click Here to Read More

Join our Solid, Semisolid, and Specialty Dosage Forms Linked-In Community
 
Parenterals
Image Placeholder
Adam Gault/Getty Images

Experts from Novo Nordisk, Baxter Discuss Technological Advances in Addressing the Challenge of Extractables and Leachables

Understanding the supply-chain challenge and coupling high-efficiency chromatographic techniques with information-rich detectors are leading to improvements in the management of extractables and leachables in parenteral drugs. Click Here to Read More

Join our Parenterals Linked-In Community
 
Other Recent Developments

Single-Use Continuous Chromatography Overcoming Limitations of Traditional Protein Purification
Continuous countercurrent tangential chromatography (CCTC) is a column-free process that provides a scalable, disposable, and cost-saving alternative to column chromatography.

Triple Quadrople Mass Spectrometry Advances Pharmaceutical Analysis
For both small- and large-molecule applications, advances in mass spectroscopy are leading to interest in this technique as an alternative to liquid chromatography.

Strategies for Managing Surplus Assets in Pharmaceutical Manufacturing
Pharmaceutical industry restructuring has created different strategies for drug manufacturers to consider in managing surplus laboratory and manufacturing assets.

New Cartridge Technology for High-Speed Filling in Parenteral Drug Manufacturing
New cartridges designed specifically for use on high-speed filling lines increase efficiency.

Reducing the Complexity of Commercial-Scale Amide Formation
Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing.

 
The Pharmaceutical Sciences, Manufacturing & Marketplace Report is a biweekly newsletter of Pharmaceutical Technology and BioPharm International, and an exclusive feature of the new Pharmaceutical Technology/BioPharm International Marketplace, an online community focused on products and services for drug development and manufacturing. The Pharmaceutical Sciences, Manufacturing & Marketplace Report provides insight in five main communities: solid, semisolid, and specialty dosage forms; parenterals; chemical API manufacturing; biological API manufacturing; and pharmaceutical analysis.  
 
Image Placeholder

Perspectives from Cynthia Challener, PhD, editor of the Pharmaceutical Sciences, Manufacturing & Marketplace Report and industry members
Image Placeholder Marketplace Report Blog
Image Placeholder

 
| Subscribe | Send Feedback | Advertise With Us | Visit pharmabiomarketplace.com |