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Pharmaceutical Sciences, Manufacturing & Marketplace Report July 24, 2013
  From Cynthia Challener, PhD, Editor, Pharmaceutical Sciences, Manufacturing & Marketplace Report
Continuous countercurrent tangential chromatography advances as an alternative to column chromatography in protein purification, and new triple quadruple and tribrid technologies expand the potential for mass spectroscopy in pharmaceutical analysis. And pharma manufacturers implement strategies for surplus assets amidst industry restructuring. Plus, the latest on cartridge technology for high-speed filling in parenteral drug manufacturing and commercialization of new amide bond-forming chemistry in API synthesis.		  
 

   
Stay current in the fast-paced world of biopharmaceutical and pharmaceutical development and manufacturing with a free subscription to the Pharmaceutical Sciences, Manufacturing & Marketplace Report.
 
Biological API Manufacturing
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Maciej Frolow/Getty Images

Single-Use Continuous Chromatography Overcoming Limitations of Traditional Protein Purification

Continuous countercurrent tangential chromatography (CCTC) is a column-free process that provides a scalable, disposable, and cost-saving alternative to column chromatography. Click Here to Read More

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Pharmaceutical Analysis
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Adam Gault/Getty Images
Triple Quadrupole Mass Spectrometry Advances Pharmaceutical Analysis

For both small- and large-molecule applications, advances in mass spectrometry are leading to interest in this technique as an alternative to liquid chromatography. Click Here to Read More
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Solid, Semisolid, and Specialty Dosage Forms
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Ion-Bogdan Dumitrescu/Getty Images
Strategies for Managing Surplus Assets in Pharmaceutical Manufacturing

Pharmaceutical industry restructuring has created different strategies for drug manufacturers to consider in managing surplus laboratory and manufacturing assets. Click Here to Read More
Join our Solid, Semisolid, and Specialty Dosage Forms Linked-In Community
 
Parenterals
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Maria Toutoudaki/Getty Images

New Cartridge Technology for High-Speed Filling in Parenteral Drug Manufacturing

New cartridges designed specifically for use on high-speed filling lines increase efficiency.Click Here to Read More

Join our Parenterals Linked-In Community
 
Chemical API Manufacturing
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Alfred Pasieka/Getty Images

Reducing the Complexity of Commercial-Scale Amide Formation

Novel, atom-efficient routes to amides from esters and carboxylic acids for more sustainable manufacturing. Click Here to Read More

Join our Chemical API Manufacturing Linked-In Community
 
Other Recent Developments

Experts from Novo Nordisk, Baxter Discuss Technological Advances in Addressing the Challenge of Extractables and Leachables
Understanding the supply-chain challenge and coupling high-efficiency chromatographic techniques with information-rich detectors are leading to improvements in the management of extractables and leachables in parenteral drugs.

New Chiral Sulfur and Phosphorous Chemistry from Boehringer Ingelheim
New routes enable the efficient synthesis of enantiopure sulfinamides and structurally and sterically diverse P-chiral phosphine oxides.

GE Healthcare, iBio, and Bio-Manguinhos/Fiocruz Advance Large-Scale Plant-Based Protein Production
GE Healthcare's partnerships with iBio and Brazil's Bio-Manguinhos/Fiocruz for a new plant-based multipurpose biopharmaceutical and vaccine manufacturing facility move plant-based protein production to the next level.

Addressing Manufacturing Challenges with Nondestructive X-Ray Imaging
Greater sophistication in 3D X-ray imaging technology raises its utility for QA/QC in manufacturing.

Technology Choices in Highly Potent Solid Dosage Manufacturing
Risk management guides decisions in facility design and operation for highly potent drugs.

 
On-Demand Webcast

USP Outlook: Key Program Activity for 2013

USP standards for the identity, strength, quality, and purity of medicines are an integral part of drug development and manufacturing. Modernization of USP monographs and development and revisions to General Chapters is a top priority for the USP Pharmacopeial Convention in 2013. In this webcast, USP experts provide the status and progress of these efforts: Monograph Modernization progress; New General Chapter content for Excipients, Analysis of Elemental Impurities, and Microbiology; and the latest on the Medicines Compendium.
Register for the on-demand webcast.

 
The Pharmaceutical Sciences, Manufacturing & Marketplace Report is a biweekly newsletter of Pharmaceutical Technology and BioPharm International, and an exclusive feature of the new Pharmaceutical Technology/BioPharm International Marketplace, an online community focused on products and services for drug development and manufacturing. The Pharmaceutical Sciences, Manufacturing & Marketplace Report provides insight in five main communities: solid, semisolid, and specialty dosage forms; parenterals; chemical API manufacturing; biological API manufacturing; and pharmaceutical analysis.  
 
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Perspectives from Cynthia Challener, PhD, editor of the Pharmaceutical Sciences, Manufacturing & Marketplace Report and industry members
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