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Pharmaceutical Sciences, Manufacturing & Marketplace Report April 24, 2013


  From Cynthia Challener, PhD, Editor, Pharmaceutical Sciences, Manufacturing & Marketplace Report
Welcome to the fifth edition of the Pharmaceutical Sciences, Manufacturing & Marketplace Report, a new biweekly newsletter of Pharmaceutical Technology and BioPharm International, and an exclusive feature of the new Pharmaceutical Technology/BioPharm International Marketplace, an online community focused on products and services for drug development and manufacturing. The Pharmaceutical Sciences, Manufacturing & Marketplace Report provides insight in five main communities: solid dosage, semisolid, and specialty dosage forms; parenterals; chemical API manufacturing; biologic API manufacturing; and pharmaceutical analysis.

In this issue, with INTERPHEX underway this week, several of our stories focus on equipment advances. Our feature covers mixing and blending equipment for solid and semi-solid dosage forms. You can also learn about visual inspection equipment for parenterals and the use of microreactors for process intensification in chemical manufacturing. Our biologic API  manufacturing story highlights the possibilities of peptoids, while our pharma analysis focus in this issue is on protein analysis, with a spotlight  on capillary-based imaging techniques for protein charge variant analysis.
  
 

     
 
Solid, Semisolid, and Specialty Dosage Forms
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Ion-Bogdan Dumitrescu/Getty Images
Optimizing the Selection of Mixing Equipment

Effective blenders provide efficient, homogenous mixing and de-aeration for wide range of formulations. Click Here to Read More
Join our Solid, Semisolid, and Specialty Dosage Forms Linked-In Community
 
Parenterals
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Maria Toutoudaki/Getty Images
Improving Performance Through Visual Inspection

Increasing production efficiency while ensuring high parenteral product quality is the goal of both manual and automated visual inspection systems. Click Here to Read More
Join our Parenterals Linked-In Community
 
Biological API Manufacturing
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Maciej Frolow/Getty Images

The Promise of Peptoids

Because peptoids are relatively easy to synthesize, have tremendous sequence diversity, and are more proteolytically stable than peptides and proteins, they have significant potential for use as APIs, drug-delivery agents, and in numerous biomedical applications.Click Here to Read More

Join our Biological API Manufacturing Linked-In Community
 
Pharmaceutical Analysis
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Adam Gault/Getty Images

Capillary-Based Methods Speed Protein Charge Heterogeneity Determination

New capillary-based imaging techniques for protein charge variant analysis are reducing development and start-up times for protein-based therapeutics. Click Here to Read More

Join our Pharmaceutical Analysis Linked-In Community
 
Chemical API Manufacturing
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Alfred Pasieka/Getty Images

Evaluating the Potential for Continuous Chemical Manufacturing and Microreactor Technology

Results of an American Chemical Society Green Chemistry Institute Pharmaceutical Roundtable survey found that there is real interest in continuous processing and the use of flow chemistry, but hurdles remain. Click Here to Read More

Join our Chemical API Manufacturing Linked-In Community
 
On-Demand Webcast

USP Outlook: Key Program Activity for 2013

USP standards for the identity, strength, quality, and purity of medicines are an integral part of drug development and manufacturing. Modernization of USP monographs and development and revisions to General Chapters is a top priority for the USP Pharmacopeial Convention in 2013. In this webcast, USP experts provide the status and progress of these efforts: Monograph Modernization progress; New General Chapter content for Excipients, Analysis of Elemental Impurities, and Microbiology; and the latest on the Medicines Compendium.
Register for the on-demand webcast.

 

Highlights from Pharmaceutical Technology and BioPharm International
Recent articles from Pharmaceutical Technology and BioPharm International

Solid Dosage, Semisolid, and Specialty Dosage Forms

Incorporating Process Analytical Technology Data into Process Control (Pharmaceutical Technology’s Equipment & Processing Report)

A Q&A with Ivo Backx, Siemens Industry Automation Division. Click Here to Read More



Parenterals

Process Analytical Technology: Advances in PAT for Parenteral Drug Manufacturing (BioPharm International)

Applying QbD and PAT facilitates process understanding in lyophilization. Click Here to Read More



Pharmaceutical Analysis

Advancing Analytical Testing and Instrumentation for Biopharmaceuticals (BioPharm International)

Click Here to Read More



Chemical API Manufacturing

Implications of Indian Supreme Court Rejection of Novartis Patent for Glivec  (Pharmaceutical Technology’s Sourcing and Management)

Click Here to Read More



Biologic API Manufacturing

Outsourcing Nontraditional Protein Expression Systems (Biopharm International, Mar)

Growth is seen in outsourcing on insect- and plant-cell-based bioproduction expression systems.Click Here to Read More



 
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Perspectives from Cynthia Challener, PhD, editor of the Pharmaceutical Sciences, Manufacturing & Marketplace Report and industry members

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