December 2015, Volume 11 Issue 12
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In the Lab
As 3-D screening and lab automation improve lead optimization, open collaborative models are breaking down long-established walls. Will the industry redefine the way it handles R&D?
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GSK will implement the Allotrope Framework for use in drug substance release and stability testing.
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Drug Development Application Handbook
A compilation of technical articles from the magazine's archives and application notes, technical information, and educational materials from the handbook's sponsors.
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Agilent Technologies and Thermo Fisher Scientific exchange instrument control drivers and software support.
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The Nexera UC Unified Chromatography System from Shimadzu Scientific Instruments was recognized with an R&D100 award.
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BMG LABTECH announces the release of a reference multi-mode HTS reader at SLAS in January 2016.
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The ReactoMate Datum controlled lab reactor system accommodates a range of vessel sizes.
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Charles River offers the Endosafe nexgen-PTS endotoxin testing system.
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Copley Scientific’s new Vertical Diffusion Cell Test System Model HDT 1000 comprises a compact unit with 10 test stations that enables the precise control of test conditions.
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KnowItAll spectroscopy software from Bio-Rad Laboratories corrects differences in spectra data.
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Outsourcing Update
Better process development is creating industry benchmarks for bioprocessing.
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Contract Services Update
With the acquisition of Medipac’s tube filling assets for effervescent tablets, Romaco can now offer the complete line configurations for effervescent tablets.
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The University of Sheffield has appointed Cobra Biologics to advance novel fusion protein technology into Phase 1 clinical trials.
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Expansions at Catalent’s Kansas City, MO, and Madison, WI facilities made in response to industry demand.
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Baxter expands capacity for lyophilized cytotoxic oncology therapies at its fill/finish facility in Halle, Germany.
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Industry veteran Mark Kontny joins board of directors at Grand River Aseptic Manufacturing.
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APIs and Excipients
Multi-component coupling reactions for the generation of heterocycles in fewer steps, and reduced processing times, cost, and waste are attracting interest.
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Ash Stevens has received FDA’s approval to manufacture Takeda’s multiple myeloma drug, ixazomib, at its facility in Riverview, Michigan.
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BASF’s new multi-product amines plant in Ludwigshafen, Germany meets growing demand for amines in various applications, including pharmaceuticals.
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Supply Chain Update
UPS’ 2015 “Pain in the Chain” survey suggests that pharma companies are getting better at product protection, cold chain and regulatory compliance, but need to improve cost control and planning for unexpected events.
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The Safe Chain Track and Trace System automates traceability for supply chain security.
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CSafe partners with Lufthansa Cargo in dedicating a fleet of RKN containers to Cool/td-Active service offering.
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