Starches are composed of the glucose polymers amylose and amylopectin. The molecular weight distribution of the polymers determines the end-use suitability. GPC may be used to determine accurate molecular weights for biopolymers, such as starches.

iMethod^TM Test for Acid Herbicides in Water
By Dr. Martin Sibum, AB SCIEX

The following method outlines the instrument requirements and expected results obtainable from this iMethodTM Test for the quantification of twenty two acid herbicides in water when using a Spark Holland Symbiosis PICO integrated online SPE / HPLC system with an AB SCIEX 4000 series LC/MS/MS instrument run in both positive and negative mode with detection limits that range from .45 to 8.0 ng/L.

Application of novel ethylene bridged hybrid particles for hydrophilic interation chromatography
By Kenneth J. Fountain, Eric S. Grumbach, Jane Xu, Christopher J. Messina, Diane M. Diehl , Waters Corporation

Novel BEH particles were found to be useful for HILIC separations. They exhibited chemical resistance superior to that of silica particles at moderate pH over the course of 2,000 injections

UPLC with On-Line SPE Technology for Water Analysis
By Claude R Mallet, Waters Corporation

Waters® UPLC with On-line SPE Technology provides analyte extraction, cleanup, concentration, separation, and detection for drinking water samples. Small sample volume requirement for trace-level analysis allow for a decrease in manual intervention during sample handling and analysis.

Delivering Repeatable, Linear, and Accurate Injection Volumes for UPLC and HPLC
By Tanya Jenkins, Waters Corporation

The ACQUITY UPLC® H-Class System uses a flow-through-needle injector design to achieve the largest injection volume range, maximize sample recovery, and provide precise injection performance.

Flash Purification of d-tocopherol & Subsequent HPLC Analysis for Sample Purity
By L Lloyd, S Ball and K Mapp, Varian, Inc

Two options now exist for purifications of crude samples. HPLC is suited to the purification of complex samples where high purity is required. Flash is suited to less complex samples or where lower purities are acceptable.

Mega Dalton Protein complexes
By David Veesler, Wyatt Technology Corporation

Recent technological advances in macromolecular crystallography led to focus on the study of more and more sophisticated biological systems, such as protein-protein complexes.

Run a difficult food sample on your IC and you stand a big chance that you will wreck the column. Of course, you can waste a lot of time on tedious sample preparation steps to eliminate undesired matrix components. Or you can go for Metrohm`s automated compact stopped-flow dialysis providing optimum separation while protecting your column from detrimental compounds.

This application note describes the use of Waters® Xevo™ TQ MS for the high sensitivity determinations of dexamethasone, at the European MRL level in food. In addition, the use of PICS acquisitions for further presence confirmation is explored.