In our March issue:
COLUMNS:
LC TROUBLESHOOTING
A View of the Selectivity Landscape
The offerings of commercially available columns for reversed-phase LC continue to expand. Are these columns similar or different compared to what is already available? Read more >>
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COLUMN WATCH
Perspectives on 1.0-mm Internal Diameter Liquid Chromatography Columns
The utility of 1.0-mm internal diameter (i.d.) columns, and the arenas in which they play a relatively strong role, are investigated. Read more >>
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BIOPHARMACEUTICAL PERSPECTIVES
CZE–MS for Characterizing mAbs
The potential of CZE–MS for the middle-up characterization of mAbs is highlighted.
Read more >>
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SAMPLE PREPARATION PERSPECTIVES
Recent Advances in Solid-Phase Microextraction
Several advances in SPME have been developed, including increasing the sorbent surface area available for extraction, accommodating direct analysis by mass spectrometry (MS), and sorbent overcoating to resist fouling by sugars, lipids, and other macromolecules present in some sample types. These advances are discussed in this month's instalment.
Read more >>
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THE ESSENTIALS
Hydrophobic Interaction Chromatography of Proteins
A discussion of hydrophobic interaction chromatography (HIC) theory and its application to the analysis of proteins and biomolecules is presented.
Read more >>
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FEATURE:
The Evolution of Foodomics
LCGC Europe spoke to Alejandro Cifuentes from the Institute of Food Science Research, in Madrid, Spain, about his current foodomics research projects, the overall state of the field, and the future of foodomics. Read more >>
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PEER-REVIEWED ARTICLES:
The Past, Present, and Future of HILIC
This article is an update on the technique of HILIC and covers recent ideas on the mechanism of separation, and how it may be manipulated to suit the separation of particular sample types. The advantages of HILIC are discussed, and also the actual and perceived disadvantages of the technique. Read more >>
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The Chromatography and Sample Preparation Terminology Guide is also featured alongside LCGC Europe's March issue.
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