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Lead Story
Gaussian peak shapes in chromatography are indicative of a well-behaved system. Such peak shapes are highly desirable from the perspective of column packing technology. Here, we discuss a number of approaches for peak shape measurement that are available in modern chromatography software, along with their advantages and drawbacks. A new "total peak shape analysis" approach is suggested that facilitates detection and quantification of concurrent fronting and tailing in peaks. Several remediation approaches are proposed that can help chromatographers analyze and improve peak shapes. read more
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The VICI DBS range of FID Gas Stations with sophisticated software control and alarm capability present the GC user with the opportunity to reap all the benefits offered by hydrogen carrier gas, whilst overcoming the safety concerns. These unique instrument combines the reliability of the VICI DBS hydrogen and zero air generators into one compact and convenient FID package.  Learn more |
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Features
The last decade has witnessed how liquid chromatography columns and instruments changed from long bulky columns with relatively large fully porous particles operated at modest pressures (100–200 bar), to short compact columns with small superficially porous particles operated at ultrahigh pressures (1200–1500 bar). This (r)evolution has resulted in a tremendous increase in achievable separation performance or decrease in analysis time but requires a good knowledge of optimal chromatographic conditions for each separation problem and, concomitant, the right instrument configuration. read more
We have entered a new stage in the era of accelerations. Moore’s law continues its expansion, increasing exponentially the computer power available. Other accelerations are remarkable, particularly easy access to cloud computing and the expansion and influence of artificial intelligence to practically all sectors of our society. read more |
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News
Researchers from the University of Seville have developed a method for the determination of pollutants in leafy and root vegetables using ultrasound-assisted extraction (UAE), dispersive solid-phase extraction (d-SPE), and liquid chromatography tandem mass spectrometry (LC–MS/MS). read more
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University students and staff get 5 years of FREE access to CHROMacademy made possible by Agilent Technologies—the world’s premiere measurement company.  Learn more |
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Application Note
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This application note outlines a simple SPE procedure for the extraction of 26 diverse per- and polyfluoroalkyl substances (PFASs) in drinking water using UCT’s polymeric weak-anion exchange SPE cartridges (ENVIRO-CLEAN® WAX). Instrumental analysis was carried out by LC-MS/MS in less than 10 minutes using a Selectra® C18 HPLC column. Overall, excellent recovery and reproducibility were obtained at the low concentrations tested.  / Learn more / |
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FEATURED PRODUCTs
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Sciencix’s HPLC PM kits are equivalent to the corresponding OEM kits. According to the company, the kits contain essential parts to keep HPLC systems performing at an optimal level. 
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WinGPC UniChrom 8.3 SR1 is a GPC/SEC/IPC software with full 21CFR11 compliance including (multi angle) light scattering or Heparin analysis. It can control more than 200 LC modules from different vendors.  / Learn more / |
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In addition to 5 µm, YMC has launched 3 µm columns of the recently introduced UNIQUE immobilised polysaccharide CHIRAL ART Cellulose-SJ using the same chiral selector found in coated products.  / Learn more / |
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Determine absolute molar mass and size, in solution, using the DAWN HELEOS II multi-angle light scattering detector. Characterize peptides, proteins, glycoconjugates and viruses; no assumptions of conformation or molecular standards.  / Learn more / |
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`Plug and play` generator to supply nitrogen for all LC/MS applications. Compact, low noise and long compressor life for continuous operation. Flow rates up to 30 lpm at 8 bar.  / Learn more / |
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The Kromasil SFC platform of chromatographic columns has been extended. These columns are shipping in organo-silane, 2-ethylpyridine, silica, cyano, and diol chemistries, with 2.5 and 5 µm particle sizes.  / Learn more / |
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