Online 2D-LC Characterization of Monoclonal Antibodies
Protein A titer analysis and weak cation exchange chromatography for charge variant analysis were combined using the Agilent 1290 Infinity 2D-LC solution for the analysis ...Read more

Fully Automated Solid-Phase Extraction of Base, Neutral, and Acid Semivolatiles in Industrial Wastewater
Traditional extraction typically involves intensive manual LLE shakes at both pH 2 and 12 for prone heavy emulsions and low recoveries, while CLLE for traditional
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Analysis of Synthetic Opiates and Novel Analgesics in Urine Using SPE and HPLC–MS/MS
Opiate abuse is drastically on the rise in the United States. In addition to traditional naturally occurring opiate compounds, forensic toxicologists also need the ability ...Read more

Multiresidue Analysis of Pesticides in Avocado with Agilent Bond Elut Enhanced Matrix Removal – Lipid by LC–MS/MS
This application demonstrates fast, effective sample cleanup for the analysis of 44 multiclass pesticides in avocado by LC–MS/MS, using a QuEChERS AOAC extraction followed ...Read more

Disulfide Bond Mapping, Comparing Innovator and Biosimilar mAbs
This application note describes a UPLC–MS^E analysis of monoclonal antibody (mAb) disulfide bonds. This study demonstrates that UNIFI — a compliance-ready software — is designed to ...Read more

Identification of Insulin Oligomeric States Using SEC-MALS
This application note shows how the combination of column chromatography (SEC/GPC) with multi-angle light scattering (MALS), dynamic light cattering (DLS), and RI detection can be ...Read more

Analysis of Pesticides in a Variety of Matrices
With the evolving market and demand for matrix-optimized transitions, the Agilent P&EP 4.0 Analyzer includes the addition of 7800 matrix-optimized transitions to provide customers with ...Read more

Advanced MS Analytical Sensitivity in Clinical Research
Here we demonstrate the analytical sensitivity gains obtained for the analysis of aldosterone in plasma using the Xevo TQ-XS Mass Spectrometer for clinical research. ...Read more