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In our March issue:
COLUMNS
LC TROUBLESHOOTING
A Numbers Game
How suitable is the column plate number for system suitability testing?
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GC CONNECTIONS
Carrier-Gas Flow or Velocity?
Chromatographers often use the term carrier-gas flow and velocity interchangeably when discussing column parameters. In LC, the two terms scale together, but in GC they do not: Doubling the flow does not double the velocity. This month's “GC Connections” investigates the reasons for this non-intuitive behaviour and how it affects best practices for gas chromatographers.
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SAMPLE PREPARATION PERSPECTIVES
Trends in Sample Prep
A comparison of the results from a new survey on sample preparation techniques to those of previous surveys, from 1991 to 2013, reveals some interesting trends.
MS – THE PRACTICAL ART
Nontargeted Metabolite Profiling
The power of nontargeted metabolite profiling is illustrated in a study focused on the determination of molecular markers in malting barley that are predictive of desirable malting quality for brewing applications.
PEER-REVIEWED ARTICLE
Peptide Analysis Using Zwitterionic Chiral Ion-Exchangers
This article discusses the potential of zwitterionic chiral ion exchangers to support peptide analysis and quality control as a flexible complementary tool to monitor the stereochemical integrity and chemical modifications.
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Pesticide Testing

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