LCGC Europe Application Note Alert Having trouble viewing this email? Click here May 2015 Hyphenated GC Sample Prep GPC   Analysis of Pesticides in Vegetables Using SFC-MS This application note demonstrates the optimization of a separation method for the determination of pesticides in a complex food matrix by supercritical fluid chromatography (SFC) with triple quadrupole MS detection. Download the app note Extraction of Vitamin D using ISOLUTE® PLD+ ISOLUTE® PLD+ Protein and Phospholipid Removal plates offer a substantial improvement in extract cleanliness compared to traditional protein precipitation techniques. This application note demonstrates their use for extraction of 25-HydroxyVitamin D with quantification using LC–MS–MS. Download the app note Capcell Pak ADME — A Novel Alternative to C18 C18 is the most popular stationary phase used in reversed-phase chromatography, but has difficulty retaining highly polar compounds. Capcell Pak ADME (ADME) is developed by firstly introducing adamantyl groups as the functional group of the reversed stationary phase of a HPLC column. The changed alkyl structure of adamantyle group provide ADME separation characteristics with a balance between moderate hydrophobicity and ultra-high surface polarity which is completely different from the conventional C18. In this study, the characteristics of ADME compared with C18 columns and its applications in the analysis of metabolite are reported. Download the app note   Analysis of Nicotine and Impurities in Electronic Cigarette Solutions and Vapour Electronic cigarettes (e-cigarettes) are growing in popularity exponentially. Despite their ever-growing acceptance, relatively little work has been done to characterize their vapour. This application note presents a gas chromatography approach for the analysis of electronic cigarette solutions and vapour. Download the app note   Determination of 11-nor-9-Carboxy-THC in Human Urine by QuEChERS and LC–MS–MS 11-nor-9-Carboxy-THC (also known as THCA or carboxy-THC) is the main secondary metabolite of THC. THCA is not psychoactive but has a long half-life. Due to this attribute, determination of THCA in urine plays an important role in the confirmation of marijuana consumption. This application utilizes the QuEChERS sample preparation technique to effectively quantitate THCA levels in human urine. Download the app note Solid-Phase Extraction and Analysis Of Organochlorine Pesticides and In-line Clean-up from Water In water samples, OCPs are monitored by the U.S. Environmental Protection Agency by various methods including methods EPA 508, EPA 608, and EPA 8081. The use of solid-phase extraction (SPE) can rapidly increase both extraction efficiency and reduce lab solvent usage. By implementing the FMS TurboTrace® ABN system with its dual cartridge functionality, an in-line Florisil cartridge can be added to perform automated extract clean-up during the elution step. Download the app note   Absolute Molar Mass in UHPLC via the μDAWN and UT-rEX Ultrahigh-performance liquid chromatography (UHPLC) enables the fast and efficient separation of biomolecular samples. Compared to standard size exclusion chromatography (SEC), UHPLC–SEC provides improved resolution, higher throughput, less solvent, and smaller sample consumption for analysis of precious biological samples. Download the app note   Go to Application Note Library Subscribe to the Application Note Alert LCE Print Edition LCE Digital Edition