In our November issue:
COLUMNS
HISTORY OF CHROMATOGRAPHY
Hamish Small: Experimenter Extraordinaire
Hamish Small spoke to André Striegel about the secrets of his success in separation science, including the development of ion chromatography, and the value of vague thoughts in scientific progress. |
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LC TROUBLESHOOTING
Keeping it Simple
John Dolan presents a practical strategy to simplify the LC troubleshooting process. |
GC CONNECTIONS
“Dead” Volume
The term “dead” volume often comes up in chromatography discussions and literature. This month, GC Connections addresses the nature of this phenomenon, when it can become a problem that affects chromatographic results, and how to understand and take control of it. |
QUESTIONS OF QUALITY
What's in a Name?
Primary record is a term that was defined by the MHRA (Medicines and Healthcare products Regulatory Agency, the UK drug regulator) in data integrity guidance issued in 2015. We explore what this term means in practice, comparing it with raw data in EU GMP and complete data in FDA GMP. We ask a simple question: Why can’t we have harmonization of terms? |
THE ESSENTIALS
Important Aspects of UV Detection for HPLC
An excerpt from LCGC’s e-learning tutorial on UV detection for HPLC at CHROMacademy.com |
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PEER-REVIEWED ARTICLE
GC–MS Quantitation of Cyanide in Human Blood
The author shares his insights into the principles and practice of implementing and improving upon the original method to quantitate cyanide at trace concentration levels in human blood matrices using automated cryogenic trapping isotope dilution static headspace gas chromatography–mass spectrometry (GC–MS). |
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