LCGC Europe Weekly Update:
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LCGC Europe - News Bulletin
 
18 December 2014
Top Story: LCGC TV: Trends in Sample Preparation
In this new short video interview from LCGC TV, Doug Raynie of South Dakota State University discusses the niche sample preparation techniques that are becoming more popular, and comments on what is needed in the future.
Biotechnology Today: The Role of Elution Gradient Shape in the Separation of Protein Therapeutics
In this article the role of the gradient in protein separations by reversed-phase and ion-exchange high performance liquid chromatography (HPLC) is discussed. To illustrate the key points, data is shown from two products.
GC–MS Analysis of an Herbal Medicinal Remedy to Identify Potential Toxic Compounds
This article from Current Trends in Mass Spectrometry discusses how you can isolate and identify the constituents of herbal medicinal products to evaluate the chemical ingredients and identify and potentially toxic compounds.


Photo Credit: Laguna Design/Getty Images		Research News: Detecting Nerve Agent Exposure
Scientists at the Norwegian Defence Research Establishment (Kjeller, Norway) in collaboration with the University of Oslo (Oslo, Norway) have presented a novel method for the quantification of nerve agent metabolites in human serum and urine by combining salting-out assisted liquid–liquid extraction (SALLE) and on-line solid-phase extraction–liquid chromatography–tandem mass spectrometry (SPE–LC–MS–MS) in the journal Analytical Chemistry.


HPLC Extra Column Volumes
It is of particular importance to reduce extra column volumes when using small volume columns or UHPLC. However, where do these extra column volumes come from, how can they be minimized, and what effect do they have on chromatography?
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