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| In this Issue |
Mary Ellen McNally on Analytical Precision
In these two new videos from LCGC TV, Mary Ellen McNally from DuPont Crop Protection addresses the issue of precision, covering the reasons why the precision of a measurement is so important and the factors that can influence the precision of an active ingredient assay. More... |
| Free BioPharma Resources |
Want to spend less time on method development and get accurate, reliable data, fast? Get free biopharma “how to” guides from Agilent to enable you to get the most from your biomolecular separations and improve your workflow. The guides include tips on method development, solvent choice, and mobile phase modification and optimization.  Learn More
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HPLC Gradient Elution – Baseline Drift
The CHROMacademy technical team was recently posed with the question of the causes of baseline drift in gradient high performance liquid chromatography (HPLC). This article explains more. More... |
UV Detector Problems
Ultraviolet (UV) detectors are the most common liquid chromatography (LC) detector, and perhaps the most reliable ones. But they are not without problems. John Dolan explains more. More... |
| LCGC E-Book: Advances in GC-MS Analysis of Pesticides |
In this new e-book, authors from the US Department of Agriculture, academia, and a European Union Reference Laboratory discuss advances in the analysis of pesticide residues using gas chromatography–mass spectrometry (GC–MS) methods.  Download PDF or Download on iTunes
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| Current features |
The Need for Speed
Sample preparation has often been viewed as the bottleneck in analytical procedures. Surveys have shown that time is typically the most frequent problem area for sample preparation procedures and that analysts can easily spend a majority of the total analysis time on sample preparation. Based on these considerations, what is high-throughput sample preparation? Do modern extraction methods adequately address the issue of time? How can we address the analytical need for speed? More... |
Teaching Old Drugs New Tricks
James Frahill, who is a Research Analyst at the Pfizer Process Development Centre (Cork, Republic of Ireland), spoke to Bethany Degg of LCGC about the role of the chromatographer in the pharmaceutical process development group at Pfizer. More... |
| Featured Product |
| The First SEC-MALS detector for UHPLC |
 The µDAWN™ is the world’s first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins. Learn more
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| On Demand Webcasts |
Monoclonal antibodies complete primary structure and biosimilarity assessment in a single analysis using CESI-MS-MS |
| Complete Inorganic Elemental Speciation Analysis Solutions for Food Safety |
| Editors' Series: Analysis and Identification of Emerging Contaminants and their Transformation Products in River Water, Urban Water, and Hospital Wastewaters: Sample Preparation and LC-MS Techniques |
| Features of Different Mass Analysers Applied to Multi-Allergen Screening |
| Suitability of Ionic Liquid GC Columns for Various Applications |
| Enhanced Detection and Confirmation in Forensic Toxicology Screening Using a UHPLC-QTOF System |
| From TLC to Flash to Prep-HPLC on BUCHI’s New All-In-One Solution – PrepChrom C-700 |
| LC Troubleshooting 3.0 - The Smart Art of LC Troubleshooting Automation |
| Qualitative and Quantitative Analysis of Protein Modifications Using CESI–MS and nanoLC-MS |
Need GC Troubleshooting Help?
CHROMacademy announces the launch of the interactive GC Troubleshooter, sponsored by Thermo Scientific.
Building on the success of our ground breaking HPLC Troubleshooter, we are excited to announce the GC version. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It’s completely free - so if you haven't tried our troubleshooter before you're in for a surprise!  Click Here |
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