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25 September 2014
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| In this Issue |
Fractal Chromatography: A New Phase in Separation Science?
The Column spoke to Tony Edge of Thermo Fisher Scientific about the development of a new type of stationary phase based on fractal-shaped particles. More... |
| E-Book Educational Series – Advances in Ion Chromatography |
This exclusive e-book assembles the top experts in ion chromatography from across the world to provide state-of-the-art views and reviews of developments and advances in this powerful separation technique.  Download PDF Today
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LCGC TV: 2D LC Methods for Analyzing Pharmaceutical Impurities
Two-dimensional liquid chromatography has moved from academia into industry. In this new video, Kelly Zhang of Genentech talks about the advantages gained by developing a two-dimensional LC method for analyzing impurities in pharmaceuticals, and gives practical examples. More... |
Column Watch: How to Choose the Correct Stationary Phase Chemistry
Many problems encountered executing high performance liquid chromatography (HPLC) methods are the result of decisions made during early method development. This instalment of "Column Watch" discusses a critical variable in method development: the choice of stationary-phase chemistry. The authors discuss two stationary phase classes, embedded polar group (EPG) and perfluorophenyl (PFP), that are highly complementary to alkyl phases from a fundamental molecular interaction point of view. More... |
The Role of Elution Gradient Shape in the Separation of Protein Therapeutics
In this article, the authors discuss the role of the gradient in protein separations by reversed-phase and ion-exchange high performance liquid chromatography (HPLC). To illustrate the key points, they show data from two products. More... |
Improving MEKC–ESI–MS–MS Analysis of Synthetic Cathinones
A team of scientists based in the Czech Republic has developed a micellular electrokinetic chromatography method coupled with tandem mass spectrometry (MEKC–ESI–MS–MS) that used salts of perfluorocarboylic acid as the volatile background electrolyte (BGE). According to the paper published in the Journal of Chromatography A, the BGE used to form micelles did not affect the electron ionization efficiency of MS. More... |
Waters Opens Global Mass Spectrometry HQ in UK
Waters Corporation (Massachusetts, USA) has opened a new custom-built mass spectrometry headquarters in Wilmslow, UK. The new headquarters took less than two years to construct from groundbreaking to completion, and bring together existing centres in the region consisting of more than 500 employees. More... |
| On Demand Webcasts |
| How to Choose the Correct Sample Preparation Approach for Modern Analytical Applications |
| Turnkey LC–MS Methods for Multiclass Pesticide Analysis Using a Comprehensive Acquisition and Processing Database |
| Editors’ Series: Environmental Forensic Investigation of Hydraulic Fracturing Fluids Used in Shale Gas Wells in the Eastern United States |
| Rapid Characterization of Antibody Biotherapeutics Using Middle-Up (Subunit) Analysis |
Need LC Troubleshooting Help?
 CHROMacademy has developed the HPLC Troubleshooter with busy chromatographers in mind. Sponsored by Thermo Scientific, in 3 simple steps you will overcome your instrument, separation and quantitation issues. It’s completely free - so if you haven't tried our troubleshooter before you're in for a surprise!  Click Here |
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| The Column |
 The Global E-zine for Separation Scientists
The global edition of The Column is delivered twice monthly with a screen-optimized format designed to improve readability. Covering topical issues, application-based articles, market reports, tips and tricks, opinion pieces and interviews, The Column is a great information resource helping readers achieve better day-to-day working practices.
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| Upcoming Webcasts |
Pushing the Limits of Chromatography with Next Generation UHPLC Technologies: How Solid Core Column and Advanced UHPLC Technologies Change the Landscape in LC Labs
Thursday 25 September 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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Analytical Separation of Antibody Drug Conjugates (ADCs) and Monoclonal Antibodies (mAbs) Using Various Chromatographic Methods
Tuesday 30 September 2014 11:00 AM PDT/ 2:00 PM EDT
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Online Sample Cleanup — A Cost-Efficient Alternative to Conventional SPE and Liquid–Liquid Extraction Methods
Thursday 9 October 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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Contact Us
Click here to contact Kate Mosford, managing editor.
Click here to contact Mike Tessalone, group publisher.
Click here to contact Gareth Pickering, sales manager.
Click here to contact Liz Mclean, sales executive.
Click here to subscribe to The Column, LCGC Europe’s and LCGC North America's digital publication. |
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