Featured Application Note:
Metabolic Patterning to Differentiate Beverages
Paul Ullucci, Marc Plante, Ian Acworth, Christopher Crafts, and Bruce Bailey, Thermo Fisher Scientific
Simultaneously measure hundreds of secondary metabolites in a sample using gradient HPLC with diode array and electrochemical detection. This metabolomic approach is used to differentiate wines and teas, as well as study adulteration and the effects of geography and varietals for fruit juices. |
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Qualitative and Quantitative Determination of Phenolic Antioxidant Compounds in Red Wine and Fruit Juice with the Agilent 1290 Infinity 2D-LC Solution
Edgar Naegele, Agilent Technologies
This application demonstrates the Agilent 1290 Infinity 2D-LC Solution for RP/RP two-dimensional chromatography. Polyphenolic antioxidant compounds in fruit juices and red wine were detected in a qualitative and quantitative manner. |
Daltonics Dispatch – Metabolomics
Dr. Aiko Barsch, Dr. Gabriela Zurek, Bruker Daltonics
This Dispatch highlights multiple examples from current research in plant, bacterial, environmental, health and single cell metabolomics.
Due to the chemical diversity of small molecule metabolites, it is impossible to study the entire metabolome using a single analytical technique or technology.
Studies will be shown based on LC-MS, GC-MS and NMR nicely illustrating Bruker´s aim of putting together the "puzzle pieces" to give a complete picture of the metabolome. |
Common Herbicides in Drinking Water
Njies Pedjie, PerkinElmer, Inc.
This application presents a sensitive and robust liquid chromatography method to test nine widely used herbicides (Figure 1), using a 3 μm UHPLC column to achieve very high throughput to reduce testing time and solvent consumption. The throughput is compared to that of a conventional C18 HPLC column. |
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Agilent J&W DB-624UI GC Column Screens Distilled Spirits by GC–MS Static Headspace
Ken Lynam, Agilent Technologies
This app note highlights the utility of using the Agilent J&W DB-624UI GC column for the screening of select distilled spirits by static headspace GC–MS. The inertness of the column delivers excellent peak shape for active aldehyde analytes in complex distilled spirit matrices. The inertness and selectivity of the DB-624UI column make distilled spirit profiling by static headspace GC very straightforward. |
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Characterization of PLGA with SEC-MALS-VIS
Stepan Podzimek, Synpo and Wyatt Technology
The characterization of PLGA by means of conventional size exclusion chromatography (SEC) is problematic because of the lack of suitable calibration standards. In this note, we show the benefits of using SEC-multi-angle light scattering (MALS) and viscometry to the absolute characterization of PLGA. |
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Automated Solid Phase Extraction and Concentration of PAHs in Water
Phillip Bassignani, FMS, Inc.
Analytically, PAHs present challenges for testing labs. Their volatile nature can make them problematic to extract without loss using manual methods. This is especially true for the evaporation or concentration of sample extracts. The following procedure utilizes the FMS PowerPrep™ SPE extraction system in combination with the PowerVap™ concentrator to extract PAHs from water. |
Extraction of Peptides From Human Plasma and Serum Using EVOLUTE® ABN Prior to LC-MS/MS
Dr Victor Vandell.
The sample preparation methodology detailed in this application note can significantly increase sensitivity and detection of peptides from biological matrices on LC/MS/MS. This application note offers the user two different elution strategies due to the extensive combination of peptides that may need to be extracted either strategy may be suitable dependent upon which peptides are relevant. |
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To advertise or have an application note inserted, contact:
Lee Noyes
+44 1244 629315 | Email
Lindsay Jones
+44 1244 629316 | Email
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