Application Note Alert
January 2012 Subscribe
Links to technical insights from sponsored Featured Application Notes on Chromatography Online.
Contact Editor
- Janet Kelsey

Featured Application Note:
Demonstrating High-Performance Quantitative Analysis of Benzodiazepines using Multiplexed SIM with High-Resolution, Accurate Mass Detection on the Q Exactive LC/MS
Kevin J. McHale, Thermo Fisher Scientific
Learn how to quantify eight benzodiazepines with LLOQs at the pg/mL level and with linear dynamic ranges of 3 to 4 orders of magnitude using the Thermo Scientific Q Exactive high performance benchtop mass spectrometer.
HPLC

High Sensitivity & Resolution with Microflow UHPLC
Khaled Mriziq, Steve Hobbs, Tina Settineri, Dave Neyer, Eksigent part of AB SCIEX

This application note describes the use of two new small diameter electrospray ionization electrodes in conconjunction with the ExpressHT-ULTRA™ microflow UHPLC system and demonstrates the improved sensitivity and faster separations achievable for High Throughput Bioanalytical LC/MS/MS.

Agilent 1260 Infinity Hybrid SFC/UHPLC System
Martin Vollmer and Markus Becker, Agilent Technologies

The Note describes the first solution capable of performing both SFC and UHPLC with a single system thus providing automated orthogonal separation power without any hardware change.
sampleprep
Extraction of Antioxidants from High Density Polyethylene (HDPE) By Pressurized Liquid Extraction (PLE)
Phil Bassignani, FMS, Inc.

This application note demonstrates the use of pressurized liquid extraction using the FMS PLE system to extract polymer additives for quatitative analysis by HPLC. Four specific additives of known concentrations were extracted from high density polyethylene (HDPE) and the recoveries measured.
Vitamin A & E Sample Prep with ISOLUTE SLE+
Victor Vandell, Gavin Jones, Biotage AB, Sweden

This application note outlines a fast, high throughput sample preparation technique for the extraction of Vitamins A & E that eliminates matrix interferences from serum allowing for mass spectral detection of the target analytes at a concentration of 100 ng/mL or less.
GPC
Molecular Weight Determination of LMWH SEC/MALS vs. SEC/ UV-RI
Wyatt Technology

Low-molecular-weight heparins (LMWHs) are obtained by fractionation or depolymerization of natural heparins. They are defined as having a mass-average molecular weight of less than 8000, for which at least 60% of the total weight has a molecular mass less than 8000.
To advertise or have an application note inserted, contact:

Lee Noyes
+44 1244 629315 | Email

Lindsay Jones
+44 1244 629316 | Email

 


You are subscribed to %%list.name%% as %%emailaddr%%. Click here to unsubscribe or edit your member profile.

To ensure delivery to your Inbox, please add %%email.list%% to your address book. If you need help doing this, click here.

Advanstar Communications provides certain customer contact data (such as customers' names, addresses, phone numbers and e-mail addresses) to third parties who wish to promote relevant products, services and other opportunities which may be of interest to you. If you do not want Advanstar Communications to make your contact information available to third parties for marketing purposes, simply call (toll free) 1-866-529-2922 at any time, or fax us at 1-218-740-6417. Outside the U.S., please phone 1-218-740-6395. Contact us by mail at Advanstar Communications Inc., Bridgegate Pavilion, 4A Chester Business Park, Wrexham Road, Chester, CH4 9QH, UK.