Current Trends in Mass Spectrometry e-newsletter:
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Presented by LCGC and Spectroscopy

November 4, 2014





Featured Articles
Application of Ambient Sampling Portable Mass Spectrometry Toward On-Site Screening of Clandestine Drug Operations
Worldwide trends in illicit drug use and production have shifted toward an increase in synthetic analogues and the emergence of new variations in their manufacture. MORE
GC–MS Analysis of an Herbal Medicinal Remedy to Identify Potential Toxic Compounds
Canola largely contains unsaturated fatty acids, thus rendering it clear in most cases after extraction and refining. However, canola can become cloudy even at room temperature. The cloudiness is thought to be largely because of the presence of wax esters transferred to the oil from the plant tissues during extraction and increased saturated fatty acid content. MORE
Application Note
Information Rich Flash Chromatography II: All-Wavelength Collection and Purity Measurement
Teledyne Isco
UV-visible detectors have been used on flash chromatography systems for several years to control the fraction collector. The purity measurements were limited to ratio measurements that required a priori knowledge of the spectra of the compound and impurities so that the correct wavelengths could be used both to collect peaks and determine purity. MORE
More Featured Articles
Large-Scale Targeted Protein Quantification Using Wide Selected-Ion Monitoring Data-Independent Acquisition
This article describes the development of a new data-independent acquisition (DIA) workflow for protein quantification that uses a mass spectrometer that combines three types of mass analyzers to achieve lower limits of detection (LOD), higher sensitivity, more accurate quantitative results, wider dynamic range, and better reproducibility than existing high-resolution accurate-mass (HRAM) tandem mass spectrometry (MS-MS) DIA workflows. MORE
Simultaneous Determination of Methylxanthines and Cotinine in Human Plasma by Solid-Phase Extraction Followed by LC–MS-MS
A multiresidue method has been developed and validated for the analysis of methylxanthines (caffeine and its metabolites) and cotinine in human plasma. MORE
Featured Products
Sensitive, Ultrafast LC/MS/MS
Offering an unparalleled combination of LC/MS/MS speed and sensitivity, Shimadzu’s triple quad LCMS-8050 dramatically improves analytical throughput while achieving the highest levels of sensitivity and quantitative performance.Learn More
Spellman’s New uX Module
Spellman introduces an ultra-compact redesign of its industry standard MNX module. The 65kV uX is 30% smaller than MNX, and has decreased weight from 3.0kg to only 2.1kg. To discuss the new uX, contact a Spellman Sales Engineer or download the datasheet at

Affordable HRAM MS Has Arrived
The new Thermo Scientific Q Exactive Focus mass spectrometer is designed to make the qualitative and quantitative power of Orbitrap-based instruments widely available to customers using Q-TOF mass spectrometry or other technologies. Learn More

New Webcasts
Future-proofing Your GC-MS Analysis: Triple Quad Workflows on Demand
Thursday, November 6, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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New Innovations in UHPLC and LCMS Workflows for the Comprehensive Characterization of Monoclonal Antibodies [mAbs] and Antibody Drug Conjugates [ADCs]
Thursday, November 13, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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Streamline Data Analysis of Tandem Mass Spectrometry for Inborn Errors of Metabolism Research
Wednesday, December 10, 2014 8:00 am PST/ 11:00 am EST/ 4:00 pm GMT/ 5:00 pm CET
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