|
| The LCGC Blog |
|
The LCGC Blog: Flow Injection Analysis Can Be Used to Create Temporal Compositional Analyte Gradients for Mass Spectrometry-Based Quantitative Analysis
Flow injection analysis (FIA) is a powerful technique for quantitative analysis, especially in conjunction with mass spectrometry (MS) detection. Kevin Schug discusses how FIA can be combined with MS using electrospray ionization and describes how the technique can be used for analyses such as binding constant determination, multipoint instrument response calibrations, and removing the dependence of measured analyze concentrations on matrix effects. More...
|
| |
More Efficient Method Development
Improve your method development productivity with Shimadzu’s Nexera Method Scouting, an exhaustive method development system that allows comprehensive method scouting using up to 96 combinations of mobile phases and columns. Scouting Solution software has intuitive, user-friendly screens for easy creation of the sequence table in seconds. In addition, a transfer program allows easy transfer of UHPLC conditions to conventional LC.  Learn more
|
|
| |
| Featured News |
|
Therapure Biopharma Acquire Plasma Protein Purification Technology from Upfront Chromatography
Therapure Biopharma (Ontario, Canada) has entered into an agreement with Upfront Chromatography (Copenhagen, Denmark) to acquire assets and associated business related to human plasma fractionation from Upfront. As part of the deal Therapure will acquire proprietary protein purification technology based on expanded bed chromatography, along with exclusive rights to commercialize the technology. More... |
| |
Fast and easy analytical to prep scale up tool
Waters OBD Preparative Columns Calculator provides mass load scaling, gradient scaling with appropriate flow rate scale-up and predicting volume consumption, calculations for split flow ratios for those using mass spectrometer driven chromatography, and focused gradient UPLC to preparative method transfer. Try this convenient tool
|
|
| |
Lung Tissue Fingerprinting
Scientists from San Pablo CEU University (Madrid, Spain) have developed a non-targeted global fingerprinting approach for lung tissue samples by performing three analytical methods — liquid chromatography coupled to mass spectrometry (LC–MS), gas chromatography coupled to MS (GC–MS), and capillary electrophoresis coupled to MS (CE–MS). Published in the journal Analytical Chemistry, the study details the development and validation of the multi-platform approach using 20 mg of lung tissue. More... |
| |
Your Chance to win an iPad Mini
LCGC Group would greatly appreciate your help by completing the following survey regarding liquid phase separation instruments and trends. We know your time is precious so every completed survey will be automatically entered into a prize draw to win an iPad Mini.
Please use only the "next" and "back" buttons at the bottom of each page to take the survey. Do not use the "forward" and "back" arrows on your browser toolbar.  Please click here to begin the survey.
Thank you
LCGC Group
|
|
| |
| Featured Article |
|
Analytical Supercritical Fluid Extraction Goes Back to the Future
The past and future development of analytical supercritical fluid extraction (SFE) is traced in terms of experimental strategies, applications, vendor support, and timely acceptance of the existing technology. The current state of the art is compared with research activity in the 1980s. New vendor activity, in terms of automation and hypenation with chromatographic separations, is discussed. More... |
| |
Ultimate Efficiency and Resolution
NEW CORTECS UPLC® Columns feature a 1.6 µm silica-based solid-core particle and ultra-low dispersion hardware, enabling higher peak capacities and thereby greater resolution and improved throughput. CORTECS Columns surpass ALL expectations.  Learn more |
|
| |
| GC Troubleshooting |
|
Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. More... |
| |
LCGC launches new e-book, Five Keys to Successful GC Methods
 Download here. |
|
| |
| Featured Product |
SEC mAb Analysis Column
The TSKgel SuperSW mAb HTP SEC column is now available from Tosoh Bioscience. This column offers high throughput separation of mAb monomer and dimer in a dramatically reduced analysis time. Its ability to withstand high flow rates at low back pressure makes the TSKgel SuperSW mAb HTP column compatible on both traditional HPLC and UHPLC systems.  Learn more. |
 |
|
| |
| New Webcast |
|
Improving GPC Reproducibility and Resolution in Polymer Characterization
Tuesday, January 14, 2014, 1:00 PM EST
Increasing challenges in polymer characterization may require methods that provide more detail on the polymers as well as greater accuracy and reproducibility. Selecting the best GPC solution – column, detector and method – can be difficult. This presentation will review column and instrument technologies that provide potential solutions to increase resolution, reduce variability in chromatographic results, and provide enhanced detail in every analysis. |
| |
|
|
|
