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November 14, 2013
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Chromatography Corner

Myths in UHPLC
The advent of ultrahigh-pressure liquid chromatography (UHPLC) and its successful commercialization in the last few years has brought forth a modern high performance liquid chromatography (HPLC) platform capable of higher speed, resolution, precision, and sensitivity. Currently, all major HPLC manufacturers offer some type of low-dispersion UHPLC products with upper pressure limits ranging from 15,000 to 19,000 psi (1000 to 1300 bar). This article describes a number of popular myths or half-truths in UHPLC and provides data that contradict or even repudiate some of these commonly held beliefs. More...
Locate Enterprise-wide Scientific Information More Effectively
Waters® Paradigm™ Scientific Search Software extends across internal information repositories, handles science objects, and indexes unstructured data – providing timely, regular, accurate and useful search results. Learn more.
Featured Article

Dr. Troubleshooting
A tribute to John Dolan, who is celebrating 30 years of writing the "LC Troubleshooting" column. His writing reflects how he spends his days: training chromatographers around the world and helping clients solve problems. Through teaching and consulting, he has handled every question imaginable, and he seems to know how to answer them all. More...
UHPLC/HPLC Excellence
Shimadzu’s Nexera X2 delivers superior, real-world performance across a wider application range while delivering unparalleled flexibility and reliability in HPLC/UHPLC analyses. Nexera X2 systems feature clean, ultrafast autosamplers, a new PDA detector, and automated solvent blending and method scouting. New Intelligent Peak Deconvolution Analysis (i-PDeA) and Intelligent Dynamic Range Extension Calculator (i-DReC) functions increase analysis speed and improve productivity. Learn more.
Featured News

EMD Millipore’s Lab Solutions Virtual Conference to Discuss Food Safety Analysis
EMD Millipore (Billerica, Massachusetts), the Life Science division of Merck KGaA (Darmstadt, Germany) will host the first Lab Solutions Virtual Conference on Tuesday, November 19, and Friday, November 20, 2013. The conference theme, “Food Safety Analysis,” will bring industry experts from around the world to discuss different aspects of this topic, including food and beverage microbiological testing, environmental monitoring and regulation, and the impact of using high-quality materials in analytical testing. More...
A Powerful Solution for Organization-Wide Scientific Information Search
Waters® Paradigm™ Scientific Search offers the solution to search for scientifically relevant information across an organization by spanning information silos, performing searches based on science objects, and adding structure to unstructured data. Learn more.
Agilent Forms Collaboration with Seoul National Hospital
Agilent Technologies (Santa Clara, California) has announced a strategic collaboration with Seoul National Hospital (Seoul, Korea). The collaboration will focus on the identification and verification of biomarkers to further the development of drugs. Under the agreement, the hospital’s department of medicine will use liquid chromatography–mass spectrometry (LC–MS) instrumentation from Agilent to further research in this area. More...
Video Application Note: Opioids in Urine
Watch this short 2 minute video to meet the Scientist behind the research and hear a brief summary of their work and the significance of their analysis. Click here.
AB Sciex Expands Operations in Singapore
AB Sciex (Framingham, Massachusetts) has announced further expansion of its presence in Singapore, with the opening of a new research and development (R&D) center. The center is an addition to the company’s existing $10 million manufacturing operations in Marsiling, Singapore. More...
Rethink Imaging Mass Spectrometry
Protea's LAESI® DP-1000 Direct Ionization System revolutionizes the way you approach imaging mass spectrometry. This powerful platform analyzes biomolecules in your sample WHERE they are and AS they are. The LAESI DP-1000 unlocks the power of your mass spec workflow, providing you with molecular distribution maps, eliminating sample prep, and offering you a broad range of new sample types. Learn more @
GC Troubleshooting

Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In 3 simple steps you will overcome your instrument, separation, and quantitation issues. It's completely free. More...
Efficient to the Core
The latest addition to the Waters family of sub-2-µm UltraPerformance LC® Columns, CORTECS™ 1.6µm Columns deliver new levels of efficiency, resolution, and throughput. With this silica-based solid-core particle designed for UPLC you can better separate your analytes, process more samples in the same amount of time, and achieve greater levels of sensitivity. Learn more.
Featured Products
Kromasil 1.8 µm UHPLC columns
AkzoNobel introduces Kromasil UHPLC columns with 1.8 µm particles. With the highest efficiency of the line and maintained selectivity, these columns can be used seamlessly throughout analytical screening, discovery, and production.
More information.
Proteins and polymers by GPC/SEC
Perfect for both protein and polymer applications, the Viscotek Triple Detector Array (TDA) employs highly sensitive refractive index, viscometer, and light scattering detectors to maximise your GPC/SEC productivity. 
Learn more
New Webcasts
Maintain your Methods, Prolong your Helium Supply, and Save Your Budget with an Innovative Helium Solution
Wednesday, November 20, 2013
10:00 am CST/ 11:00 am EST/ 16:00 GMT.
In this web seminar, we discuss a simple and safe helium solution that enables you to continue your analyses while keeping your methods intact, validation-effective, and regulation-compliant while alleviating helium supply concerns and extensive supply costs.  Learn how this technology optimizes the flow and usage of helium when your instrument is idle, as well as during the analytical run, to eliminate potential waste typically observed in standard GC operations.  Find out how to extend the lifetime of one helium cylinder to over 14 years under certain conditions and experience significant savings in both helium supply needs and financial costs throughout the lifetime of your GC-MS instrument.
Editors’ Series: Fundamentals, Optimization and Practical Aspects of UHPLC: Series 3:  Practical aspects of UHPLC
Tuesday, December 3, 2013
9:00 AM EST/ 2:00PM GMT/ 3:00PM CET.
A scientific, unbiased series of webinars on UHPLC. This three-part series of "must-attend" events for those who have heard about, or use UHPLC, and want to know more.
Special Section
Spotlight Event

Lab Compliance Week
Overcome GLP/GMP Challenges for Lab Compliance, Quality and Validation Professionals

Dec. 3-5, 2013
Philadelphia, PA

> Download Brochure
> Register

Related Articles

- A Three-Pronged Template Approach for Rapid HPLC Method Development
- The Edge of Failure
- Trends in Sample Preparation

More in Pharma/Bio

Upcoming Events

18–20 November 2013
Eastern Analytical Symposium & Exposition
Somerset, NJ
» Visit the website
3–5 December 2013
QbD Quality by Design
Philadelphia, PA
» Visit the website
3–5 December 2013
Lab Compliance Week
Philadelphia, PA
» Visit the website
3–5 December 2013
Stability Testing, Part of Lab Compliance Week
Philadelphia, PA
» Visit the website