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LCGC North America | e-Separation Solutions
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October 2010
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Technology Forum

HPLC/UHPLC
While high performance liquid chromatography (HPLC) is the standard liquid separation technique in most analytical laboratories, ultrahigh-pressure liquid chromatography (UHPLC) is being implemented as a choice for faster, high-resolution analyses and cross-platform systems are now available. Participants in this discussion are Ling Bei and Dave Lentz of EMD Chemicals, Sergio Guazzotti of Thermo Fisher Scientific, and Elizabeth Hodgdon and Jeannine Jordan of Waters Corp.
More...

New Product Video available demonstrating the Total-Prep™ solution for POPs analysis.
FMS introduces the first and only "Total Solution" Sample Prep system that combines three sample prep processes into one economical package. The TRP-Total-Rapid-Prep™ performs extraction, sample clean-up and concentration for six samples simultaneously in a few hours, producing the highest recoveries and best results for all analytes. For a product video demonstration visit: Total Prep Video , For additional information please visit: Total Prep website

 

Featured Articles

Qualitative and Quantitative Metabolite Identification for Verapamil in Rat Plasma by Sub-2-µm LC Coupled with Quadrupole TOF-MS
An effective metabolite identification study should ideally include both qualitative and quantitative information that for both identifying metabolites, and determining the rate of clearance and the metabolic routes of the parent drug.
More...
 
Bare Silica Has a Future in Supercritical Fluid Chromatography
A current study that experimentally compares five bonded phases with bare silica for the SFC separation of a 19-component mixture of polar analytes is reported.
More...
 

Agilent MVS can have a headline of Agilent's Multi-Vendor Services Program.

Agilent Multi-Vendor Service provides comprehensive maintenance, repair and compliance support for all major LC, GC and MS models, regardless of manufacturer. We've expanded our job description to help you simplify service administration and get the highest quality service for your lab. No matter what name is on your instrument, trust Agilent Multi-Vendor Service for all your support needs. Learn more.

Featured Products

World’s Only No Compromise UHPLC
At 19,000 psi, Shimadzu’s modular Nexera meets all analysis requirements: conventional, ultra-high speed, high resolution, multidimensional, etc. with no compromise in data integrity. Features include the world’s fastest injection (10-second cycle time), near-zero carryover (0.0015% without rinsing), maximum resolution with the widest pressure/flow range, excellent injection reproducibility (0.25% area %RSD), and more. Visit www.ssi.shimadzu.com/LCGCIA

 
 

GPC/SEC Columns for proteins
WTC columns have all of the finest features of first-class SEC columns for protein separations. They are made of the highest quality silica with well-controlled pore size and highly reproducible surface chemistry. As a result, these columns provide high resolution, extended lifetime, excellent lot-to-lot reproducibility, and a full range of pore size selections. Learn more...

 
 
UHPLC Sample Prep Filtration
Increase column life and improve chromatographic results with Pall’s 0.2 µm Acrodisc® syringe filter for Ultra High Performance Liquid Chromatography (UHPLC) sample prep filtration. Available in 13 and 25 mm sizes, the UHPLC filter is ideal for UHPLC sample prep and buffer filtration when using column packings
< 2 µm.
Learn more...
 
 

Glass columns - "reloaded"

KNAUER Bioline high resolution glass columns for bioseparations have been designed to overcome some common glass column drawbacks such as their delicateness and little pressure resistance. Bioline glass columns withstand 100 bar (1450 psi), allow packing with ease, and feature axial compression and a built-in cooling/heating jacket. Read more...


 

Polyphenol Analyzer for F&B

With the introduction of a new dedicated Polyphenol Analyzer by Antec, sensitive analysis of polyphenols at low costs in Food & Beverage Industry has become possible in routine.

www.myantec.com


CHROMmunity
A service by LCGC and CHROMacademy
Forum and Networking site for Chromatographers.

Forums:
  • Is there a rule of thumb for converting conditions going from HPLC to UHPLC?
  •  
  • What if a compound has 2 pKa's?
  •  
  • Using RP-HPLC to calculate Log D
  •  
  • The Best HPLC
  •    
    Blogs:
  • Kevin Schug looks at the worrisome trend of younger students losing interest in science.
  •  
  • Merlin K. L. Bicking shares his experiences from his training class last week in Kampala, Uganda.
  • Join in the Big Chromatography Conversation.     Free Registration.»


    Featured Webcasts & Podcasts

    Increase LC–MS Throughput and Improve ROI for Biological Samples— Tuesday, October 26, 2010 at 11:00 AM EST, 8:00 AM PST
    We will present a case study based on this strategy as a tool to analyze 45 drugs of abuse in performance horses.
    More...
     
    LC and LC–MS in the Pharmaceutical Industry: Small Molecule Quantitative Analysis and Matrix Effects— Wednesday, November 3, 2010, 8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
    Dr. Kevin A. Schug, Assistant Professor at the University of Texas at Arlington will discuss fundamental and applied studies of LC and LC-MS for trace quantitative analysis of small molecules and metabolites.
    More...
     
    Developing Better Methods for Reversed Phase HPLC (Part 2)— On Demand
    The Essential Guide from LCGC’s CHROMacademy presents Part 2 of our series on Developing Better Methods for Reversed Phase HPLC.
    More...
     
    Molecular Imaging for Localization and Distribution of Proteins, Peptides, Drugs and Metabolites by Mass Spectrometry— On Demand
    This presentation will detail the use of both MALDI-TOF and FTMS mass spectrometers to measure the tissue distribution of a variety of proteins, peptides, lipids, or small molecule drugs and metabolites in various tissues.
    More...
     
    Supercritical Fluid Chromatography in Theory and Practice
    In this podcast series, we’ll be discussing how users can benefit from supercritical fluid chromatography (SFC) in their laboratories.
    More...
     
    Optimizing Chromatographic Conditions for Protein Analysis with the ACQUITY UPLC H-Class Bio System
    Biopharmaceutical proteins are large, complicated molecules and demand multiple modes of analysis to ensure complete characterization of the sample.
    More...



     
    Upcoming Events

    27–30 October 2010
    45th ACS Midwest Regional Meeting Wichita, KS.
    » Visit the website

    7–10 November 2010
    3rd International Conference on Polyolefin Characterization Shanghai, China.
    » Visit the website

    14–18 November 2010
    Pharmaceutical Sciences World Congress 2010
    New Orleans, LA.
    » Visit the website

    15–17 November 2010
    Eastern Analytical Symposium and Exposition (EAS)
    Somerset, NJ.
    » Visit the website

    30 November–4 December 2010
    ACS 66th SWRM (Southwest Regional Meeting) and 62nd SERMACS (Southeast Regional Meeting)
    New Orleans, LA.
    » Visit the website

    15–20 December 2010
    Pacifichem 2010- The Int. Chemical Congress of Pacific Basin Societies
    Wichita, KS.
    Honolulu, HI.
    » Visit the website

    19–21 January 2011
    IFPAC 2011: 25th International Forum Process Analytical Technology
    Baltimore, MD.
    » Visit the website

     

     

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