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October 2, 2014
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Featured Article

Evaluating Particle Size and Back Pressure in Peptide Mapping by UHPLC
Ultrahigh-pressure liquid chromatography (UHPLC) columns are used in peptide mapping to improve the resolution of highly complex peptide mixtures. It is commonly assumed that small particle columns increase performance, but this is not always the case. Under some conditions, when factoring in maximum back pressure, small particle columns may not provide the maximum peak capacity or fastest method. This study presents a comparison of peak count, column length, and resolution between core–shell and fully porous UHPLC columns. More...
Do You Want a Cost Effective Replacement For Your Existing Concentration and Evaporation Techniques?
Attend a free Webinar on October 15th 2014 to learn how. The new FMS SuperVap family are standalone automated waterless concentration/evaporation systems and are available in vessel sizes of 250ml, 50ml with 500ul, 1 ml tips and direct to GC vial as well as 60ml, 40ml, 20ml, 4ml and 2ml vial sizes to meet all of the laboratory’s needs.  Register for the Webinar to learn more about how the SuperVap Automated Concentration System can help your laboratory.
Featured Video

Michal Holčapek on Trends in LC–MS
In this new video from LCGC TV, Michal Holčapek from the University of Pardubice in the Czech Republic describes the requirements of "fast LC–MS" and areas where the technique can be applied in industry. More...
More Efficiency, More Free Time
All you expect, and more. The new Agilent 1290 Infinity II LC sets new benchmarks in analytical, instrument and laboratory efficiency. You may find yourself with extra time on your hands. Meet the next generation of Agilent UHPLC:
Featured Interview

Upcoming Eastern Analytical Symposium Integrates Art and Science
The 2014 Eastern Analytical Symposium and Exposition (EAS), taking place November 17–19 in Somerset, New Jersey, promises attendees a comprehensive program of educational and networking opportunities for analytical scientists. In advance of the event, LCGC spoke to EAS President Anne-Françoise Aubry, and EAS Program Chair Andrew V. Teplyakov about what attendees can expect this year. More...
Advanced SEC made simple
Malvern Instruments has released an update to their OmniSEC GPC/SEC software. Selectable "polymers" or "proteins" user interfaces with simplified workflows and integration with Waters Empower® improving productivity. For total confidence in your macromolecular characterization, it’s now even easier to incorporate the Viscotek SEC-MALS 20 detector into your existing system to determine absolute molecular weight with no calibration or assumptions. Learn More
GC Troubleshooting

Need Help with GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In three simple steps you will overcome your instrument, separation, and quantitation issues. It's completely free. More...
Antibody Drug Conjugate (ADC) Characterization
New RPC, HIC, IEX and SEC columns for analyzing antibody drug conjugates, include an advanced RPC polymer chemistry, PolyRP™-1000Å, available from The Nest Group, Inc.. For non-denaturing analyses, Zenix™ SEC, PolyPROPYL A™ HIC, and PolyCAT AWCX columns separate aggregates, deamidation products or oxidized forms of your antibody. Try one of our ADC characterization approaches today! The Nest Group, Inc. - "Not Just Columns ... Answers!"
Featured Products

Ultrapure water for Analytical & Life Science Research
ELGA's award winning PURELAB® Chorus delivers consistent water purity for your life science or analytical research from ultrapure Type I through to Type III general grade water.
Learn More
Shiseido HPLC Columns
CAPCELL CORE is a polymer-coating type core-shell column of 2.7-μm particle with 1.7-μm solid core and 0.5-μm porous layer. CAPCELL CORE provides high-speed and improved separation in UHPLC as well as conventional HPLC.
Learn More
Serving All Lab Needs
Proton OnSite’s S-Series lab server produces the equivalent of four cylinders of better-than-UHP grade hydrogen every day to support various analytical applications. Cut cost & improve efficiency with one safe solution.
Learn More
Applications for Rapid Separations
Solve your UHPLC separation challenges faster and more effectively than ever before with the combination of the Thermo Scientific™ Accucore™ Vanquish UHPLC columns and the Vanquish UHPLC system.
Learn More
On Demand Webcast

Next Generation UHPLC Technologies: Change the Landscape in LC
Automated Solid Phase Extraction for the Environmental Testing Laboratory
Utilizing PepFinder Software for Interrogation of LC-MS Peptide Map Data of Biotherapeutics
Good Practices to Control Contamination in Elemental Analyses
Rapid Characterization of Antibody Biotherapeutics Using Middle-Up (Subunit) Analysis
Achieving Highly Efficient and Rugged Separation in Ultra-High Pressure Liquid Chromatography Using 2.0-µm Fused-Core Columns
New Webcasts
Online Sample Cleanup — A Cost-Efficient Alternative to Conventional SPE and Liquid–Liquid Extraction Methods
Thursday, October 9 , 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
The Development of a Method for Arsenic Speciation and the Use of Ion Chromatography as a Solution for Separation
Tuesday, October 14 , 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
Add Isotope Ratio Information to Your Research
Wednesday, October 22, 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
Upcoming Events
October 5–8
SPICA 2014
Base, Switzerland
» Visit the website
October 14–15
Gulf Coast Conference 2014
Galveston, TX
» Visit the website
November 5–7
30th Montreux LC/MS Symposium
Charleston, SC
» Visit the website
November 17–19
Eastern Analytical Symposium and Exposition (EAS)
Somerset, NJ
» Visit the website