The LCGC Blog
As the fall semester starts, I begin my 13th year as a chemistry professor. Let me get right to the point—if you do not love this job, you will hate it! Read more
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The TurboTrace® PFC (Perfluoralkylated substances) SPE system is designed to streamline your laboratory's workflow and increase productivity by automating the manual steps in your sample preparation process. It is designed for high throughput and tough sample matrices. It isthe first automated solid phase extraction system made specifically for PFC extraction and concentration. Effective at reducing background contamination, extraction and concentration of aqueous samples takes less than two hours.
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LCGC TV
Reed Harris from Genentech discusses the early attempts to use failure mode and effects analysis (FMEA) scores in quality by design (QbD). He also touches on the complexity of using ranking systems for determining critical quality attributes (CQAs). Read more
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The Proton OnSite Hydrogen Lab Server produces up to 18.8 SLPM of ultra-high purity hydrogen gas sensing demand and adjusting production accordingly. When installed into a gas system, it can serve numerous floors and rooms with a constant, pure stream of hydrogen gas. This compact generator produces the equivalent of four cylinders of hydrogen every day – eliminating the cost and hazards associated with delivered gas.  Learn more
Featured Articles
A quick step-by-step guide for optimizing GC temperature programming. Read more
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C18, C18 ExRS (High Carbon Load), C8, Phenyl, PFP, HILIC - YMC-Triart is not one, but SIX distinct phases with complementary selectivity. Based on a high strength hybrid silica particle, all YMC-Triart phases are stable over an extended pH range, elevated temperature, and high pressure. Particle sizes include 1.9, 3, 5, 10, 15 and 20 µm. Column inner diameters range from 0.075 to 300 mm.  Learn more
You have to be careful when adjusting gradient conditions.
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View the growing list of zwitterionic, HILIC column applications from The Nest Group™. The list describes  separations of nucleosides, nucleotides, lipids, phospholipids, amino acids, cell metabolites, and artificial sweeteners. Included literature references provide an overview of the capabilities of these silica and polymer based HILIC chemistries. Try iHILIC® Fusion columns or SPE cartridges today! The Nest Group, Inc. - "Not Just Columns ... Answers!"
Featured Articles, Continued
In this study, general extract screening of food storage materials was done with nontargeted analytical methods to understand what analytes could potentially leach into food or beverages. GC and mass spectral deconvolution effectively separated analytes within the complex mixture and TOF-MS provided full mass range spectral data for identification. This workflow can be used for confident characterization of components present as extractables from food packaging materials. Read more
In this review, the authors discuss mixed-mode chromatography stationary phases. An overview of applications using mixed-mode chromatography is described, as well as the increased interest in mixed-mode systems for two-dimensional chromatography. Read more |
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FEATURED PRODUCTS
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The µDAWN™ is the world's first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins.  Learn more |
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CAPCELL CORE, a new polymer-coated core-shell resulting in high separation efficiencies and fast analyses. Capcell Core is available in C18, AQ, Hilic and PFP chemistries.  Learn more |
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With full mass range resolving power >25,000, and our novel Encoded Frequent Pushing™ for increased sensitivity, you’ll be able to analyze even your most complex samples more confidently than ever before.  Learn more |
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New CIA Advantage-xr instruments from Markes International for the automated high-throughput analysis of trace-level 'air toxics’ and other pollutants from air streams up to 100% relative humidity, sampled using canisters or bags.  Learn more |
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Quadrex 007-624 GC columns are a low to mid-polarity cyanopropylphenyl dimethylpolysiloxane GC capillary column, equivalent to the USP G43 phase type. 007-624 columns are specifically designed for volatile organic compounds and residual solvent applications.
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Meet your most stringent purification processes with flash cartridges that deliver the fastest speed, unsurpassed resolution, purity and yield, with the greatest loading capacity.  www.sorbtech.com |
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The TSKgel UP-SW3000, 2 μm SEC column provides accurate mass determination using non-denaturing SEC/MS. Additionally, the column shows no signs of particle shedding or sample carryover.  Learn more |
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The GC FID Station Delivers Hydrogen and Zero Air from a Space Saving Enclosure. Hydrogen to 1 lpm and Zero Air to 5 lpm. GC Instrument Sits On Top Generator.  Learn more |
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Application Notes
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This application note describes a combined approach of analytical method development and method transfer by direct emulation of different target HPLC systems.  read more |
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The advantage of UV spectroscopy as an analytical method to detect protein aggregation is that it is non-destructive and uses low sample volumes, minimal sample.  read more |
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