The LCGC Blog

Automated Method Development in Liquid Chromatography

The ability to rapidly screen stationary phases through column-switching capabilities provides significantly greater efficiency in method development than was previously possible. The approach does require some additional hardware and software. And, while such capabilities may limit the ability to expand one’s literary knowledge during excessive months in the laboratory developing separation methods, real progress to key decision points for method optimization can be realized instead. Read more

Monodispersity Matters to Jordi Resolve GPC Columns

New generation Jordi GPC columns prepared with monodisperse 100% DVB particles with precisely controlled particle diameter and finely controlled pore structure provide high efficiency, high separation capacity, low back pressure with greater bed stability & clean light scattering backgrounds. Resolve columns allow separation from 500 to 12 million g/mol (PS equivalent). Learn more

LCGC TV

LCGC TV: HILIC Method Development: Scouting Runs and Software

In HILIC the retention times are much more sensitive to small changes in mobile phase composition than in reversed-phase LC. Gert Desmet from the Vrije Universiteit Brussel discusses the potential implications for the use of software for HILIC method development. Read more

Mott has introduced their PerfectPeak® HPLC Static Inline Mixers that reduce baseline noise with superior solvent mixing. Designed using cutting edge 3D print technology, these mixers provide a low maintenance, high quality solution to cartridge replacement mixers that can sometimes leak or cause poor gradient mixing. Pressure rated to 20,000 psig, our mixers are constructed of 316L SS material and quickly install into any HPLC system. Learn more

Featured Article

New Advice on an Old Topic: Buffers in Reversed-Phase HPLC

A model set of analytes and selected applications are used to demonstrate the effects that buffers can have on the selectivity of a separation and the sensitivity of a reversed-phase analysis when using MS detection. Read more

One Path….No Variables

Your chromatography purification: method develop or optimization. Choose the wrong stationary phase and you’re on the wrong path: No separation, resolution, yield, or purity ….or create side chain reactions and impurities requiring more purification steps!
Sorbtech’s expertise in stationary phases & applications from small molecule to biomolecules, pharma to materials puts you on the Right Path eliminating the Variables.
Call: 1-866-Sorbtec or email: [email protected] to contact a specialist.