The LCGC Blog
Until recently, I hadn't heard of ternary or quaternary gradients being used for many years. They have gained a reputation for being somewhat difficult to reproduce—less robust, if you like. Read more
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To meet demands for a lower cost method for the sample cleanup of dioxins and PCBs that requires little financial investment and eliminates hardware, features of the PowerPrep® system to deliver consistent, fast, reliable results with short turnaround times and low background using FMS pre-packaged columns have been deployed. The SemiPrep™ with a simple semi-automated approach uses a minimum amount of solvent and zero DCM producing excellent results.  Read more
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LCGC TV
HILIC retention is a highly complex mechanism. Gert Desmet from the Vrije Universiteit Brussel discusses his recent research into predicting retention in HILIC. He also reviews whether isocratic and gradient retention predictions could be made based on a limited number of runs. Read more
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New! Zwitterionic, LC-MS columns for metabolomic applications are now available from The Nest Group™. Download the  brochure describing separations of nucleotides, phospholipids, amino acids, cell metabolites and artificial sweeteners, which includes literature references for an objective overview of capabilities for these silica and polymer based HILIC chemistries. Try iHILIC® Fusion columns or SPE cartridges today! The Nest Group, Inc. - “Not Just Columns ... Answers!”
Featured Articles
Get the most from your method by considering what you want it to do and setting appropriate chromatographic parameters. Read more
Practical examples of how to correct for matrix effects in food testing to obtain reliable quantitative data using LC–MS and GC–MS. Read more
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Featured Interview
Capillary electrophoresis (CE) is routinely used for chemical and biochemical analysis methods, and recently the technique has been implemented on microchips. R. Scott Martin, a professor and chair of chemistry at Saint Louis University, has been investigating ways to improve these techniques for years. He recently spoke to us about his research coupling microchip electrophoresis with electrochemical detection, coupling continuous flow with microchip electrophoresis with valving, coupling microchip CE with microdialysis sampling and electrochemistry, and more. Read more
More Featured Articles
We consider some of the details associated with preparing a column for storage, with an eye toward choices that will pay dividends in future use. Read more
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Application Notes
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New generation Jordi Resolve 13 μm GPC columns prepared with monodisperse 100% DVB particles with precisely controlled particle diameter and finely controlled pore structure provide. read more
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This application note shows the seamless transfer of a method for the analysis of beta-blockers from an Agilent 1260 Infinity LC to an Agilent 1260 Infinity II LC.  read more
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