The LCGC Blog
Hydrophilic Interaction Chromatography can be a very useful tool in our analytical armory, however there are some practical peculiarities to this chromatographic mode which need to be understood in order to ensure success. Read more
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Featured Articles
How much of a change can you make to a USP method without revalidating the method? Read more
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Restek is bringing the speed and reliability of Raptor LC columns into the HILIC realm with the addition of the Raptor HILIC-Si column. The Raptor HILIC-Si column simplifies the switch to HILIC because it delivers rugged Raptor performance, provides SPP column speed for faster analyses than traditional FPP silica columns, retains polar compounds without ion-pairing reagents, and is fully reliable, efficient, and selective with LC-MS compatible mobile phases. Learn more
In this three-part series, we assess how UHPLC evolved into a modern platform. We start by examining the most important features common to most commercial instruments. Read more
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Register today for the International Symposium on GPC/SEC and Related Techniques taking place October 2nd-5th in New Orleans, Louisiana, USA. Come learn about the latest innovations in polymer characterization from leading experts at Dow, DuPont, Arkema, DSM Resolve, and more. Don't miss this opportunity to discuss novel solutions that address current analytical challenges facing the polymer characterization industry. Learn more at www.gpcevent.com.
Headspace SPME combined with GC–MS for the qualitative and quantitative analysis of terpenes in cannabis offers several advantages compared to other methods. It does not require the use of organic solvents, does not coextract matrix, and provides additional means of peak identification and purity using spectral data. It is also a nondestructive method. Read more
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New! Zwitterionic, LC-MS columns for metabolomic applications are now available from The Nest Group™. Download the brochure describing separations of nucleotides, phospholipids, amino acids, cell metabolites and artificial sweeteners, which includes literature references for an objective overview of capabilities for these silica and polymer based HILIC chemistries. Try iHILIC® Fusion columns or SPE cartridges today! The Nest Group, Inc. - "Not Just Columns ... Answers!"
LCGC TV
You can't compromise in quality or cost in any analysis. Susan Olesik from The Ohio State University discusses how green chemistry does not involve any compromises. She also describes homogenous edge-plane carbon for use in reversed-phase HPLC. Read more
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Build Your Pesticide Library With SPEX CertiPrep Pesticide Mixes! Many new pesticides are now being tested using GC/MS and LC/MS and GC techniques to determine even minute amounts of pesticide residue in environmental samples and food products. SPEX CertiPrep is the leader in offering HPLC, GC, GC/ MS, and LC/MS pesticide CRMs designed to work within the EPA, AOAC, FDA, and international analytical testing methods. Learn more
Featured Articles, Continued
Simultaneous, enantiomer-specific identification of chiral molecules in multicomponent mixtures is extremely challenging. With mass-selected photoelectron circular dichroism (MS-PECD) using an electron–ion coincidence imaging spectrometer, a compound can be identified as chiral without the need for any prior enantiomeric separation or enantiomer-selective complexation. Read more
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Application Notes
Ephedra alkaloids are phenethylamines that occur naturally in plants, including the herb Ma Huang used in traditional Chinese medicine. The aim of this study was to develop a multi-analyte procedure for the extraction, cleanup, and quantification of the ephedra alkaloids in functional foods and natural products. read more |
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The advantage of UV spectroscopy as an analytical method to detect protein aggregation is that it is non-destructive and uses low sample volumes, minimal sample. read more |
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