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| LCGC TV Featured Video |
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LCGC TV: The Pros and Cons of GCxGC
Two-dimensional gas chromatography has advanced considerably since its first emergence in the late 1980s and its first applications for the hydrocarbon fingerprinting of crude oils. In two new short videos from LCGC TV, Frank L. Dorman of Penn State University talks about the evolution of GCxGCand the key advantages and disadvantages of the technique, including why fear of its complexity gets in the way of its broader use.
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Helium is a Non-Renewable Resource. Conserve it
There is a global helium shortage that has caused prices to soar. Many GC users are switching to hydrogen as a carrier gas. Hydrogen provides many advantages over helium including, higher resolution, shorter run times, longer column life, and cost savings. A hydrogen generator is a safe, convenient solution. Download this step by step guide on switching to hydrogen as a carrier gas. Learn more |
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| The LCGC Blog |
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A View of Separation Science Research at a Czech Conference
The United States woefully underfunds international collaborations with the Czech Republic. Yet, it is a country that produces excellent scientists who are distinctly passionate about science, and who have been educated to demonstrate not only a strong mastery of chemistry basics, but also superb knowledge of the integration of high-level mathematics and computer programming skills into their science. One need not look very far in the separation science and mass spectrometry (MS) fields in the United States to find eminent leaders with roots in the Czech Republic. More...
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LiChrosolv® Solvents for Liquid Chromatography
With their low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in ‘gradient grade’ as well as ‘isocratic grade’. This enables you to minimize the gradient effect of the solvent involved – for example in enantiomeric separations on chiral phases.  Learn more |
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| Featured News |
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Gerstel Form OEM Agreement with Spark Holland
Gerstel GmbH & Co. KG (Mülheim an der Ruhr, Germany) and Spark Holland (Emmen, The Netherlands) have announced an original equipment manufacturer (OEM) agreement. The agreement will allow Gerstel to develop and market fully integrated automated dried blood spot (DBS) technology from Spark Holland that recently received a US patent. DBS or dried matrix sampling is an emerging tool for bioanalysis, and is particularly useful in the clinical and pharmaceutical laboratory, requiring 5–15 μL of sample for each analysis. More...
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Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory.
The ACQUITY UPC2 System is a holistically designed convergence chromatography system that utilizes liquid carbon dioxide as the primary mobile phase. The system leverages the chromatographic principles and selectivity of normal-phase chromatography while providing the ease-of-use of RPLC, enabling you to address routine and complex separations challenges while delivering sensitivity and throughput never before possible.  Learn more |
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LC–MS Deconstructs the "Poppy Seed Defense"
Scientists at King’s College London in London, UK, have discovered a new metabolite in urine that is an indicator of heroin (3,6-diacetylmorphine) intake. The paper published in Drug Testing and Analysis suggests that the marker can be used to rule out poppy seed ingestion and confirm illicit drug intake. More...
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Simplified HILIC separations from a world leader in HILIC
New, eHILIC chemistry from The Nest Group, Inc. addresses both acidic and basic, polar analyte separation challenges. Whether the goal is to reduce their interaction or enhance it, our ERLIC capability facilitates separations by polar differences.  Try our ERLIC separation - "Not Just Columns ... Answers!". |
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| LC Troubleshooting |
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Need Help With LC Troubleshooting?
A free interactive LC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In three simple steps you will overcome your instrument, separation and quantitation issues. It's completely free. More... |
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| Application Note |
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Improve CE-SDS Results with Automated Sample Preparation
Michael Kowalski, Clarence Lew, James A. Thorn, and Mehul P. Vora, Beckman Coulter Life Sciences
This application note presents an automated preparation method for the analysis of IgG protein samples by CE-SDS. The method improves results, reduces sample preparation variability, and samples show reproducible peak areas and migration times. More... |
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Waters introduces the ACQUITY QDa Detector
The future is now separated from the past. Imagine a lab where all analytical scientists can acquire high-quality mass spectral data. On their own. Within their existing workflows. Across every sample. Without training. Waters imagined just that and introduces the ACQUITY QDa Detector. Click Here |
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| New Webcasts |
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Applying Best-in-Class HPLC Column Technologies to the Analysis of Proteins and Biotherapeutics
Tuesday, March 18, 2014 11:00 AM EDT
First, discover how BIOshell Fused-Core HPLC columns help you with your peptide and protein separations. As Dr. Hillel Brandes explains, “BIOshell Fused-Core particle columns get your work done faster or, if already fast enough, provide more reliable results.” Then, learn from Dr. Kevin Ray how stable labeled antibody internal standards are used to determine the pharmacokinetic (PK) properties of mAbs and Fc-fusion therapeutics. |
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Editors’ Series: Prospects and Pitfalls in Metabolomics: From Study Designs to Interpreting Data in Biomedical Applications
Wednesday, March 19, 2014
11:00 AM EDT
In this web seminar, Professor Oliver Fiehn of UC Davis will explain the importance of different steps in the metabolomic workflow and how to avoid the most dramatic pitfalls along the way — from defining a suitable hypothesis to choosing the most suitable analytical platforms, to interpreting the data — and all the steps in between. |
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The Use of Solid Core Technology in the Pharmaceutical Environment
Thursday, March 25, 2014 8:00 AM PDT/ 11:00 AM EDT/ 3:00 PM GMT
This webinar will provide the tools for successful introduction of solid core chromatography. It will explain how the technology works and which columns to choose for specific areas and stages in the pharmaceutical pipeline. |
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Increasing Laboratory Efficiency through a Harmonized Compliance Solution
Thursday, March 27, 2014 8:00 AM PDT/ 11:00 AM EDT/ 3:00 PM GMT/ 4:00 PM CET
Analytical instrument qualification (AIQ) procedures that laboratories must carry out to comply with the regulations of the U.S. FDA and similar regulatory agencies worldwide can be complex, costly, and fraught with risks. In this webcast, you will review the key aspects of AIQ, learn about the latest regulatory requirements, and discover how a harmonized solution can make consistent compliance easier for your laboratory. |
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HPLC for Pharmaceutical Analyses: Succeed with Sample Filtration and Optimized Water Quality
Wednesday, April 9, 2014 8:00 AM PDT/ 11:00 AM EDT
Do you perform HPLC in a pharmaceutical discovery or development operation? Attend this webinar, and you’ll learn valuable strategies for maintaining clean baselines, improving run reproducibility, and prolonging column life. Our speakers will guide you through choosing the sample filtration platform to match your workflow stage and throughput needs and understanding the impact of water quality on chromatography results. |
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High Resolution MS Screening and Quantitation Method for Contaminants in Dietary Supplements
Thursday, April 10, 2014n 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
Learn from the FDA’s Lukas Vaclavik about the analysis of pharmaceutical and plant toxin contaminants in herbal dietary supplements. |
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| Upcoming Events |
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1–4 April 2014
analytica 2014
Munich, Germany
» Visit the website |
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3 April 2014
Chromatography Forum of the Delaware Valley Annual Symposium
Washington, PA
» Visit the website |
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11–15 May 2014
HPLC 2014
New Orleans, LA
» Visit the website |
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18–23 May 2014
38th International Symposium On Capillary Chromatography and the 11th GCxGC Symposium
Riva del Garda, Italy
» Visit the website |
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25–28 May 2014
ExTech 2014
Chania, Crete, Greece
» Visit the website |
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20–23 July 2014
PREP 2014 Symposium on Preparative and Process Chromatography
Boston, MA
» Visit the website |
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