The LCGC Blog
A short treatment of what to consider when choosing the appropriate sample solvent so you can be better informed when developing, optimizing, transferring, or troubleshooting your GC methods. Read more
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New generation Jordi GPC columns prepared with monodisperse 100% DVB particles with precisely controlled particle diameter and finely controlled pore structure provide high efficiency, high separation capacity and low back pressure with greater bed stability. 5µm Resolve columns allow separation from 500 to 3,000,000 g/mol (PS equivalent). For higher molecular weights, up to 12 million, Jordi offers its Resolve DVB 13 µm columns.
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How certain are you that you have done that assessment well? Reed Harris from Genentech discusses how the uncertainty scale helps to determine the most important factors when assessing critical quality attributes. Read more
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MethodsNowTM features step-by-step instructions for analytical and synthetic methods in areas like pharmacology, HPLC, food analysis, natural product isolation analysis and water analysis.  Click here to learn more
Featured Article
We examine the experimental factors that control peak resolution. Read more
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While conventional calibration for gel permeation (GPC) and size-exclusion chromatography (SEC) are useful for polymer characterization, there are inherent disadvantages in these analyses. Adding multi-angle light scattering (MALS) detection can help overcome the challenges faced with single-detector chromatography. For more complex polymers, asymmetric flow field-flow fractionation (AF4) offers additional capabilities.  Download the eBook
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Agilent’s solvent bottles have been redesigned for easier use and safer handling, lowering the risk of accidents in the lab. These ergonomic solvent bottles are compatible with your InfinityLab LC Series systems.  Learn more
Featured Articles
In this installment of the History of Chromatography column, Keith Bartle talks about his proudest scientific achievements. Read more
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New! Semi-Reusable BioPureSPN™ TARGA® RPC spin columns, capable of desalting from 100% water, improve recovery of polar molecules prior to LC-MS. For glycans, nucleotides or peptides. Try our color-coded  BioPureSPN TARGA C18 spin columns or cartridges today! The Nest Group, Inc. - “Not Just Columns ... Answers!”
What are the best methodologies for demonstrating comparability? Read more
This accurate, precise method overcomes matrix interference problems Read more
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FEATURED Application note
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This application outlines a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) technique that has been optimized to extract common prescription and illicit drugs from liver prior to analysis by LC-MS/MS.  Learn more |
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