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The LCGC Blog
I'm often asked to help with the development of column "screening" platforms and automated development systems. While this covers a large amount of analytical science there are some common elements to this type of approach, perhaps the most important of which is column selection. Unsurprising given that "selectivity" is the most powerful tool we have in chromatography and we all know that the best way to optimize selectivity is to choose the most appropriate stationary phase.
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What if your ion chromatography system could operate without taking a break? Discover how capillary ion chromatography can keep your laboratory running 24/7 while reducing eluent waste and disposal costs. Learn More
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Featured Articles
In the environmental analytical chemistry literature, the topic of matrix interferences and matrix effects has not been addressed in a fundamental way. Here, we examine which methods appear to have a tendency for matrix interference and suggest ways to reduce the problem. Read more
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Join CASSS for the 7th International Symposium on Higher Order Structure of Protein Therapeutics taking place on April 9-11, 2018 in Providence, Rhode Island. HOS 2018 will include informative presentations by industry experts, interactive discussions, and networking opportunities. Learn more and register now!
A number of approaches for peak shape measurement are available in modern chromatography software. We discuss the advantages and drawbacks of those approaches, and present a new concept, "total peak shape analysis." Read more
A common challenge in LLE is the formation of emulsions. Several approaches can address the problem. Or, one can try an alternative technique. Read more
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The Proton OnSite Hydrogen Lab Server produces up to 18.8 SLPM of ultra-high purity hydrogen gas sensing demand and adjusting production accordingly. When installed into a gas system, it can serve numerous floors and rooms with a constant, pure stream of hydrogen gas. This compact generator produces the equivalent of four cylinders of hydrogen every day – eliminating the cost and hazards associated with delivered gas. Learn more
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Three main points summarize the best ways to be successful in GC: capillary GC is clean GC; practice, practice, practice; and be a student of GC. Read more
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Enhanced beds of PROTO™ 300 & TARGA® RPC chemistries eliminate particles which can plug capillary columns. "Equilibrate & Store" or "Run & Save" for reduced sample losses of very small samples. Try our storable BioPureSPN™ RPC & HILIC spin columns in our new, lower cost configurations today. LEARN MORE at The Nest Group, Inc. - "Not Just Columns … Answers!"
Featured News
The American Chemical Society (ACS) 2018 National Awards will be presented at a ceremony on March 20 in conjunction with the 255th ACS National Meeting in New Orleans. Read more
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Application Note
Easy-to-use and fully integrated method for the determination of drug to antibody ratios (DARs) of antibody-drug conjugates (ADCs).
• Easy-to-use method for the determination of drug to antibody ratios of ADCs
• Open access automation solution that is specifically designed for biomolecule sample preparation
• BioConfirm software provides automatic calculation of the average DAR for all forms of the ADC
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PharmaFluidics' game-changing chip-based chromatography column for nano-LC, lets you detect more molecules in tiny, complex biological samples. High resolution separations are obtained, perfect for lipidomic, metabolomic and peptide profiling. Learn more |
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