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In our June issues:
COLUMNS
Column Watch
The Promise of Metal–Organic Frameworks for Use in Liquid Chromatography
David S. Bell
What can metal–organic frameworks offer for liquid chromatography?
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The Denver X-ray Conference is the world's leading forum for scientists working in the field of X-ray materials analysis. The conference provides a unique mixture of sessions and workshops on training, education and applications on state-of-the-art techniques and future developments in X-ray analysis. The meeting also hosts an exhibit of the leading manufacturers of X-ray equipment who exhibit the latest products, services and software related to X-ray analysis.
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LC Troubleshooting
Peak Purity in Liquid Chromatography, Part III: Using Two-Dimensional Liquid Chromatography
Dwight R. Stoll, C.J. Venkatramani, and Sarah C. Rutan
Here, we see how 2D-LC can solve coelution problems that are difficult or impossible to address using peak purity tools or curve resolution methods.
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Perspectives in Modern HPLC
Antibody–Drug Conjugates: Perspectives and Characterization
Rowan E. Moore, Kelly Broster, Ken Cook, Kyle D'Silva, Eric Niederkofler, Aaron O. Bailey, Jonathan Bones, and Michael W. Dong
Comprehensive characterization of ADCs requires increasingly powerful approaches consisting of small- and large-molecule techniques.
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IVT's Stability Testing Europe allows attendees to review core FDA and ICH guidance to breaking down the latest regulatory policies, including a brand new updated WHO draft guidance for API and finished drug stability testing. Don't miss the chance to participate in hands-on training for small molecules, biologics and medical devices to harmonize global systems and enhance stability programmes.
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Focus on Biopharmaceutical Analysis
Analytical Characterization of Biotherapeutic Products, Part I: Quality Attributes
Anurag S. Rathore, Ira S. Krull, and Srishti Joshi
To ensure the reliable and accurate characterization of biotherapeutics, an
arsenal of orthogonal analytical techniques is needed.
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The Essentials
HPLC Troubleshooting: Autosampler Contamination
With autosamplers, we need to be extra careful to avoid contamination.
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PEER-REVIEWED ARTICLES
Profiling Nonionic Surfactants Applied in Pharmaceutical Formulations by Using Comprehensive Two-Dimensional LC with ELSD and MS Detection
Gerd Vanhoenacker, Mieke Steenbeke, Koen Sandra, and Pat Sandra
Comprehensive 2D-LC using HILIC and reversed-phase LC is a robust tool to characterize nonionic ethoxylated surfactants in pharmaceutical formulations.
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As the landscape continues to face an influx of regulations surrounding the reliability, consistency and accuracy of analytical methods and data, it is critical for the biopharmaceutical industry to adhere to new regulatory expectations.
Analytical Procedures & Methods Validation Europe provides a comprehensive understanding of regulatory trends and requirements, "hands-on" training for executing procedures that survive the lifecycle and solutions to challenges within the laboratory.
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Chromatography Fundamentals, Part II: Thermodynamics of Liquid Chromatography: Energetics
Howard G. Barth
We examine the connection between the distribution coefficient and Gibbs free energy, and contributions from enthalpy and entropy.
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Biomimetic Chromatography to Accelerate Drug Discovery: Part I
Klara Valko
Drug discovery can be accelerated by chromatographic profiling of analogs by measuring their nonspecific binding to proteins and lipids.
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THE APPLICATION NOTEBOOK
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Address the Paradigm Shift in Regulatory Inspections
Thursday, June 28, 2018
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Optimize Your Lab's Performance with On-Site Nitrogen Gas Generation
Wednesday, June 27, 2018 at 2pm EDT | 1pm CDT | 11am PDT
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Maintaining a Competitive Edge in an MS Core Lab
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Automated Sample Preparation for a More Efficient and Reproducible Phosphopeptide Enrichment Workflow
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Enhanced GC-MS Sensitivity and Robustness for Routine Determination of Phthalates in Vegetable Oil
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Data Integrity Oversight Through Analytics Leveraging Metrics for Periodic Review
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Development of a New Online Micro-Viscometer for APC and UHPLC Applications
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Real-Time, High-Sensitivity Food and Flavor Analysis Using Direct MS
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Chromatographic Method for Preservatives following the United States Pharmacopeia Monograph Modernization Initiative
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Editors' Series: Wastewater Analysis as a Tool for Public Health Assessment and Law Enforcement
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Drug Antibody Ratio (ADC) Calculations Made Easy and Simple
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Implementing GC-HRAM MS for More Efficient and Effective Routine Pesticide Residues Analysis
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