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In our April issue:

COLUMNS

Column Watch
New Liquid Chromatography Columns and Accessories for 2019
David S. Bell
Our annual review of new liquid chromatography columns and accessories.

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  Featured Product
Merlin Microseal for GC
Reduce GC downtime and eliminate septum coring by replacing your inlet septa with the Merlin Microseal. Ideal for automated runs and SPME analysis, it lasts for thousands of injections. Learn more
LC Troubleshooting
Reversed-Phase Liquid Chromatography and Water, Part II: Re-equilibration of the Stationary Phase Following Gradient Elution
Dwight R. Stoll
Re-equilibrating a reversed-phase stationary phase following aqueous gradient elution can be achieved much faster than you think.

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Gaining Operational Efficiencies in Drinking Water Analysis
Tuesday, April 30, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Perspectives in Modern HPLC
New HPLC Systems and Related Products Introduced in 2018–2019: A Brief Review
Michael W. Dong
New HPLC and MS systems: A review of instrumentation trends and the current market along with new instruments, modules, chromatography data systems, and related software.

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Determination of Pesticides as Defined by California State Recreational Cannabis Regulations
Friday, April 26, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Focus on Environmental Analysis
Trends in Water Analysis
Laura Bush
In this interview, Thomas Letzel of the Technical University of Munich considers the current state of water analysis, looking at recommended techniques, the growth of nontargeted screening, and multi-disciplinary collaboration.

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Characterizing CQAs of Biopharmaceutical Products: A Comprehensive Workflow Approach to Common Biopharmaceutical Tests
US and Europe: Wednesday, April 24, 2019 at 9am EDT | 2pm BST | 3pm CEST
US: Wednesday, April 24, 2019 at 2pm EDT | 1pm CDT | 11am PDT
Asia-Pacific: Thursday, April 25, 2019 at 8:30am IST | 11am CST | 12pm JST
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The Essentials
Electron Ionization in GC–MS
We provide a succinct explanation of electron ionization for GC–MS and illustrate the fundamentals of ion formation.
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Flash Chromatography: Introduction, Tips, and Techniques
Wednesday, April 17, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Feature
Data Integrity Focus, Part IV: Are Raw Data and Complete Data the Same?
R.D. McDowall
The meaning of the terms raw data and complete data are explored. One term is from EU GMPs and the other is from US GMPs. Do they mean the same thing?

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PEER-REVIEWED ARTICLE

Chromatography Fundamentals, Part VI: The Gaussian Distribution and Moment Analysis
Howard G. Barth
How well do Gaussian-shaped profiles represent injected solute peaks after they are eluted through a chromatographic column? This question is explored along with a discussion of moment analysis for determining retention time, variance, and shapes of peaks.

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ON DEMAND WEBCASTS
Native Mode Mass Spectrometry Analysis
On Demand
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The Importance of Computer System Validation for Regulated Systems
On Demand
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Improvement of Both Legacy and New HPLC Methods with Superficially Porous Particle Columns
On Demand
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A Multi-mode LC Approach to Biosimilar Characterization
On Demand
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LIVE WEBCASTS
Flash Chromatography: Purification Tips and Techniques
Wednesday, April 17, 2019 at 11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Characterizing CQAs of Biopharmaceutical Products: A Comprehensive Workflow Approach to Common Biopharmaceutical Tests
North America and Europe: Wednesday, April 24, 2019 at 9 am EDT | 11 am PDT | 1 pm CDT | 2 pm BST | 3 pm CEST
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Achieving Greater Chiral LC and SFC Analysis and Purification Success
Thursday, April 25, 2019 11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Determination of Pesticides as Defined by California State Recreational Cannabis Regulations
Friday, Apr. 26, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Gaining Operational Efficiencies in Drinking Water Analysis
Tuesday, April 30, 2019 at 11 am EDT | 8 am PDT | 4 pm BST| 5 pm CEST
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Native Mode Analysis of mAbs and ADCs- Intact Workflow Solutions for Characterizing Biomolecules by HIC and SEC Chromatography Techniques
North America: Tuesday, April 30, 2019 at 11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
Europe: Wednesday, May 1, 2019 at 9 am BST | 10 am CEST
Asia Pacific: Thursday, May 2, 2019 at 8:30 am IST | 11 am CST | 12 pm JST
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If you would like to submit an article to LCGC, contact Laura Bush, Editorial Director - [email protected]

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