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In our March issues:
COLUMNS
Sample Prep Perspectives
Recent Advances in Solid-Phase Microextraction, Part I: New Tricks for an Old Dog
Douglas E. Raynie
A look at recent advances in SPME, such as increasing the sorbent surface area available for extraction, accommodating direct analysis by mass spectrometry, and sorbent overcoating to resist fouling by sugars and lipids

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Focus on Results. Uninterrupted.
What if your ion chromatography system could operate without taking a break? Discover how capillary ion chromatography can keep your laboratory running 24/7 while reducing eluent waste and disposal costs.
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Better Living Through (Flavor) Chemistry: Vacuum Ultraviolet Spectroscopy as a New Tool for GC Analysis of Terpenes in Flavors and Fragrances
Live Webcast: Wednesday, March 28 at 11:00am EDT
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LC Troubleshooting
Eluent Preparation for Hydrophilic Interaction Liquid Chromatography, Part II: pH, Buffers, and Gradient Elution
Dwight R. Stoll and Claudia Seidl
Certain details related to mobile-phase preparation that can be assumed in reversed-phase LC separations can be much more consequential in HILIC.

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  Featured Product
Sensitive, Reliable Microflow LC-MS/MS
Obtain microflow sensitivities with the confidence of analytical flow using Shimadzu’s Nexera Mikros, which accommodates a wide range of flow rates, from micro (0.1 µL/min) to semi-micro (500 µL/min). Learn more
GC Connections
A Compendium of GC Detection, Past and Present
John V. Hinshaw
Gas chromatography makes use of a wide variety of detection methods, which really shine when deployed properly. Here’s guidance for how to choose the right one for your analysis.
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Monitoring Volatile Organic Compounds Using GC and GC-MS: Meeting the Challenge of Protecting the 981-Mile Ohio River
Live Webcast: Tuesday, March 20 at 11:00am EDT
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The Essentials
Optimizing SEC for Biologics Analysis
Parameters such as pore size, column dimensions, temperature, flow rate, and mobile phase are important to consider when developing SEC methods.
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Increase Throughput Using Magnetic Sector GC–HRMS
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PEER-REVIEWED ARTICLES

Scaling LC Methods Using Superficially Porous Particle Stationary Phases
Gregory K. Webster and Mathew A. Gragg
Because not all laboratories have UHPLC systems, reverse scaling of methods from UHPLC to HPLC is often needed, particularly in the pharmaceutical industry. The use of superficially porous particles can facilitate this process.

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Fundamentals of Advanced Detection in Size Exclusion Chromatography for the Characterization of Polymers and Proteins
On Demand
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Chromatography Fundamentals, Part I: Thermodynamics of Liquid Chromatography: The Distribution Coefficient
Howard G. Barth
This article, the first in a series on chromatography fundamentals, discusses the cornerstone of all chromatographic techniques—the distribution or equilibrium coefficient—and its influence on liquid chromatographic separations.

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Data Integrity Concerns: Challenging Chromatographic Analyses
Live Webcast: Tuesday, March 27 at 10:00am EDT
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NEW WEBCASTS
The CHROMacademy Essential Guide to: Top Tips to Improve Reproducibility and Sensitivity in Solid Phase Extraction
Thursday, 22 March, 2018 at 11 am EDT | 8 am PST | 1500 GMT | 1600 CET
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Sensitive Forensic Screening for Drugs of Abuse in Human Urine Using Single Quadrupole GC-MS and a Simple Solid Phase Extraction
Thursday, 29 March, 2018 at 8 am EDT | 1300 BST | 1400 CEST
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New USP <1058> Analytical Instrument Qualification Regulations: What the 2017 Requirements Mean and How to Comply
North America: Wednesday, April 4, 2018 | 1 pm EDT | 12 pm CDT | 10 am PDT
Europe: Wednesday, 4 April, 2018 | 0900 BST | 10000 CEST
Asia Pacific: Thursday, 5 April, 2018 | 0800 IST | 1030 CST | 1130 JST
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Easing Your Solid Phase Extraction Headaches
Tuesday, 10 April, 2018 at 11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
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Process and Specialty Gas Analysis Applications of Direct Mass Spectrometry
North America Live: Wednesday, April 18, 2018 at 11 am EDT | 10 am CDT | 8 am PDT
Europe Live: Wednesday, 18 April, 2018 at 1300 BST | 1400 CEST
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ON DEMAND WEBCASTS
Getting Started with GC Analysis for Cannabis
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Address the Paradigm Shift in Regulatory Inspections
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An Approach to Method Validation for Direct Mass Spectrometry
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