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Chromatography Corner |
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Lucie Nováková on the Development of Bioanalytical Methods for Pharmaceutical and Clinical Research
Production of new drugs continues to increase, placing pressure on analytical scientists to develop new bioanalytical methods to characterize and ensure quality control and safety. LCGC spoke to Lucie Nováková of Charles University in Prague, Czech Republic about the development, optimization, and challenges of bioanalytical methods as well as future emerging research areas.
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A New Paradigm for Peptide Mapping
For biotherapeutic proteins to be effective, they must be produced in biologically active forms with proper folding and post-translation modifications (PTMs). Thermo Scientific™ PepFinder™ software provides accurate identification, in-depth characterization, and relative quantitation of biotherapeutic and other proteins from mass spectrometric data. It provides automated workflows for glycopeptide identification, disulfide bond mapping, and quantification of PTMs.  Learn more |
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| Featured Product |
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The New Standard in UHPLC
The Thermo Scientific™ Vanquish™ UHPLC system takes high-end UHPLC to a new level. The system addresses the needs of chromatographers performing state-of-the-art UHPLC, all within a single integrated and fully biocompatible platform. This system is designed to offer better separations, more results and easier interaction than ever before.  Learn more
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| Chromatography Solution Center |
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Resources for Pharma Analysis
We all know that pharmaceutical analysis is full of complexity. The Chromatography Solution Center, developed by LCGC in coordination with a leading supplier, can help — by providing a variety of articles, application notes, videos, and other resources — updated monthly. This month's offering includes advice on:
Application Note: An Improved HPLC Method for the Separation of Norethindrone and Mestranol with Progesterone as Internal Standard
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GC Troubleshooting |
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Need Help With GC Troubleshooting?
A free interactive GC Troubleshooter is now available at CHROMacademy, sponsored by Thermo Scientific. In three simple steps you will overcome your instrument, separation, and quantitation issues. It's completely free.
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| On Demand Webcasts |
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Clinical Applications of LC-MS: Development and Research Application of a Highly Sensitive LC-MS Method for Quantification of a Cholesterol Protein in Plasma
LC Troubleshooting 3.0 – The Smart Art of LC Troubleshooting Automation
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| Upcoming Webcasts |
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Turnkey LC-MS Methods for Multiclass Pesticide Analysis Using a Comprehensive Acquisition and Processing Database
Wednesday, August 27, 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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Utilizing PepFinder Software for Interrogation of LC-MS Peptide Map Data of Biotherapeutics
Thursday, September 17, 2014 8:00 AM PDT/ 11:00 AM EDT/ 4:00 PM BST/ 5:00 PM CEST
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