LCGC Pharmaceutical Focus
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LCGC North America | e-Separation Solutions
February 23, 2016
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Chromatography Corner

Can SBWC Replace HPLC in Pharmaceutical Analysis?
Subcritical water chromatography (SBWC) is seen as an increasingly enticing prospect to replace high performance liquid chromatography (HPLC) in industrial settings because of its low costs and environmental impact. Yu Yang of East Carolina University, in Greenville, North Carolina, has conducted research into this process for two decades. He recently spoke to LCGC about his work, why companies should consider SBWC, and its role in pharmaceutical analysis.
Application Note
Transferring a Method for the Characterization of PTMs from the UltiMate 3000 BioRS System to the Vanquish Flex UHPLC System
Michael Menz, Carsten Paul, Evert-Jan Sneekes
Demonstrating a successful transfer of an HPLC protein deamidation monitoring method from the Thermo Scientific™ UltiMate™ 3000 BioRS UHPLC to the Thermo Scientific™ Vanquish™ Flex UHPLC system. Learn more
Chromatography News
Quantifying Methylergonovine Using LC–MS-MS
A team of researchers from China and the USA has developed a liquid chromatography coupled to tandem mass spectrometry (LC–MS-MS) method for quantifying methylergonovine (ME), a semi-synthetic ergot alkaloid used for the treatment and prevention of postpartum hemorrhage (PPH), in human plasma.
Featured Article

Image credit:
Joe Zugcic, Joe Zugcic Photography		 Ghost Peaks from Nitrile Glove Contamination in Reversed-Phase LC Drug Analysis
An investigation into the root cause of new peaks revealed an unusual source of contamination. This article explains more.
 
Featured Products
Thermo Scientific™ Vanquish™ Flex UHPLC; the newest product in our biocompatible chromatography system series. Thermo Scientific™ UltiMate™ 3000 BioRS System
Built on our award winning Vanquish UHPLC platform, Vanquish Flex UHPLC is designed for maximum application flexibility to meet all of the necessary applications for the biopharma market. Learn more The Ultimate 3000 BioRS System offers true bio-UHPLC capabilities with completely stainless steel-free flow path, near-zero dead volume. Learn More
 
   New Webcast
Development Partners for BioPharma: Are You Getting What You Need?
Thursday, February 25, 2016
8 am PST | 11 am EST | 4 pm GMT | 5 pm CET
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