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The Column
August 17, 2017
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FEATURES

Volatile Separation: A Low-Density Approach

Separating and quantifying both volatile and nonvolatile compounds in complex mixtures is a costly and time-consuming process presenting significant technical challenges. Fabrice Gritti discusses his team's solution to this problem, combining high-vacuum technology and low-density fluid chromatography (LDFC) with carbon dioxide as a mobile phase for a rapid and complete baseline separation of both volatile and nonvolatile compounds. read more


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Fast, Reproducible Pesticide Residue Analysis in Food

Traditional techniques used to perform the extraction of pesticides from food matrices are time consuming, solvent intensive and can deliver inconsistent results. The need for economical, fast, reproducible testing protocols exists. Perform consistent extraction of pesticides for analytical quantitation in 10 minutes. The PLE can dramatically improve reproduciblity of results, speed and cost of extractions. Learn more

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INCOGNITO

Chromatographers: What's Your Problem?

Incognito wants to know how you deal with problems that arise in the laboratory. read more


FEATURES

A Guide to Modern Comprehensive Two-Dimensional Gas Chromatography

A short overview of the theory and practice of the rapidly developing field of two-dimensional gas chromatography (GCxGC) is presented. read more


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New Publication: Analytix Reporter

From the makers of The Reporter and the makers of Analytix comes... Analytix Reporter. Separation and wet chemistry techniques all in one scientific journal. Whether you are a previous subscriber or want to become a new reader, be sure to fill in your contact details to receive the inaugural edition and all subsequent editions of the new Supelco journal, the Analytix Reporter from MilliporeSigma. www.SigmaAldrich.com/newsletters


Application Notes

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Vitamin D Metabolite Analysis in Biological Samples

A rugged and reliable sample preparation method using Agilent Captiva EMR—Lipid for 96-well plate based in situ protein precipitation and pass-through lipid cleanup.. Read more


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DCM-Free, Semi Automated, Sample Cleanup for POPs Analysis

To meet demands for a lower cost method for the sample cleanup of dioxins and PCBs that requires little financial investment and eliminates hardware, features.. Read more


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Screening of Pesticides in Food Using GC–QTOF

This application note describes the use of a novel high-resolution, low energy EI capable GC–QTOF to screen pesticides and other contaminants in food matrices.. Read more

LCGC TV

Enhancing HILIC with “Enhanced Fluidity”

Susan Olesik from The Ohio State University discusses how applying “enhanced fluidity” to HILIC makes the technique greener and better. She also describes an “enhanced fluidity” method that was developed for a gradient HILIC separation of ribonucleic acid nucleotides and nucleosides. read more


NEWS

New Vaccine Quality Assessment Assay Developed Using Conformation-Dependent Antibodies Coupled to SE-HPLC

Researchers have developed and validated a stability- and potency-indicating assay protocol for high-throughput quality assessment of vaccines consisting of recombinant virus- “like” particles (VLPs) using conformation-dependent antibodies coupled to size-exclusion high performance liquid chromatography (SE-HPLC). read more


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eBook: Practical Copolymer Analysis using GPC/SEC and Related Techniques

Gel permeation chromatography/size-exclusion chromatography (GPC/SEC) is a powerful tool for determining the complete molar mass distribution of macromolecules. Recent design advances are creating new opportunities to use GPC/SEC for challenging analyses such as copolymers. In this eBook, experts discuss how several GPC/SEC methods may improve copolymer sample characterization. Learn about dual-detection methods, polymer liquid adsorption chromatography, 2D chromatography, and more. Download the eBook


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