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Formulary, A peer-reviewed drug management journal for managed care and hospital decision-makers
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FormularyJournal.com

May 6, 2011

Formulary
Home Medication Safety FDA Actions Latest News Policy Watch Drug Watch
In This Issue
Opioid-related mortality associated with daily dose for nonmalignant pain
FDA approves first meningococcal vaccine for infants and toddlers
Low A1c level linked to higher risk of mortality in elderly
FDA approves Zytiga for late-stage prostate cancer
FDA approves new treatment for type 2 diabetes
Meeting News
Long-term combo naproxen/esomeprazole safe, effective
Consider ER oxymorphone in patients with chronic low back pain, comorbidities
AMCP names 4 new members to board

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Fingolimod (Gilenya) was recently FDA approved in the treatment of relapsing remitting multiple sclerosis (RRMS). How is your health system covering or planning on covering this new oral disease-modifying therapy (DMT)?

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2) We will be/are covering it only for patients who have failed injectable DMTs (either an interferon or glatiramer acetate).

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Digital Edition

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Opioid-related mortality associated with daily dose for nonmalignant pain

A daily dose of opioids for nonmalignant pain is strongly associated with opioid-related mortality, and doses of 200 mg or more of morphine or equivalent are associated with a particularly high risk, according to a recent study published in the April issue of Archives of Internal Medicine. Read full article.

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FDA approves first meningococcal vaccine for infants and toddlers

FDA approved the use of meningococcal (A, C, Y, W-135) polysaccharide diphtheria toxoid conjugate vaccine (Menactra, Sanofi Pasteur) in children aged as young as 9 months for the prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroups A, C, Y, and W-135. Read full article.

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Low A1C level linked to higher risk of mortality in elderly

Hemoglobin A1C levels below 6% are associated with a small but significant increased risk of mortality in elderly patients, according to a retrospective cohort study published online in Diabetes Care. Read full article.

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FDA approves Zytiga for late-stage prostate cancer

FDA has approved abiraterone acetate (Zytiga, Centocor Ortho Biotech), an oral, once-daily medication for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have received prior chemotherapy containing docetaxel. Read full article.

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FDA approves new treatment for type 2 diabetes

FDA approved linagliptin (Tradjenta, Boehringer Ingelheim and Eli Lilly) tablets, used with diet and exercise, to improve blood glucose control in adults with type 2 diabetes. Read full article.

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Meeting Coverage

Long-term combo naproxen/esomeprazole safe, effective

No new or unexpected safety issues occurred during long-term treatment with a fixed-dose combination of naproxen and esomeprazole magnesium (Vimovo) in patients at risk of NSAID-associated upper gastrointestinal ulcers, according to data presented at the annual meeting of the American Academy of Pain Medicine, National Harbor, Md. Read full article.

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Consider ER oxymorphone in patients with chronic low back pain, comorbidities

In patients with chronic low back pain with comorbidities such as hypertension, diabetes, and cardiovascular disease, extended-release oxymorphone (Opana ER, Endo Pharmaceuticals) may be a safe and effective alternative, according to a study presented at the annual meeting of the American Academy of Pain Medicine, National Harbor, Md. Read full article.

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AMCP names 4 new members to board

The Academy of Managed Care Pharmacy recently installed 4 new members to its board of directors. The new board members were sworn in April 29 at AMCP's 23rd Annual Meeting & Showcase in Minneapolis. Read full article.

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Top 5 Web Stories

  1. FDA Pipeline Preview, April 2011 (Salix, Protalix, Amyvid, indacaterol, Istodax, Mucin 1 targeting peptide GO-203-2c, Intercept plasma, Lomitapide, Liver cell therapy)

  2. Metastatic breast cancer: A review of current and novel pharmacotherapy

  3. Belimumab: A B-lymphocyte stimulator inhibitor for-systemic lupus erythematosus

  4. Health reform controversies pose new challenges for drug plans and healthcare providers

  5. Intensive glycemic management leads to higher mortality in type 2 diabetes mellitus patient
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