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Clinical Considerations for Derm NPs and PAs
image description here This month’s highlights center prescribing spironolactone for patients with hormonal acne, using biologics to treat hidradenitis suppurtiva, and questioning the conventional wisdom of the progression rate and risk of cutaneous lupus converting to systemic disease. Read my comments below, and the stories for further insights!. Read my takeaways and the full stories below!
— Joe Gorelick
 
CLINICAL CONSIDERATIONS
 
Spironolactone for hormonal acne
Do you prescribe Spironolactone for the treatment of hormonal acne? What is your starting dosage? Spironolactone has proven to be an effective and safe treatment option for hormonal acne. In fact, for healthy patients laboratory potassium monitoring is often not performed.
Read more to familiarize yourself with these and other updates in pediatric dermatology.
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Biologics offer promise for hidradenitis suppurativa treatment
Hidradenitis Supperativa (HS) is a devastating disease for patients and is difficult to treat effectively for health care providers. Adalibumab is the only approved biologic indicated for the treatment of HS in the US and, as Dr. Kerdel discusses, represents a novel therapeutic option for the HS patient population. We now appreciate that the likely etiology of HS is inflammatory vs infectious so targeting the inflammatory cascade via biologic therapy has shown efficacy. Dr. Kerdel also discusses additional specific inflammatory pathways that may be targeted with other biologic agents such as secukinumab, infliximab, and anakinra to treat HS. These agents are currently under investigation and may result in much needed additional approved therapies for HS.
Learn more.
 
Skin lupus can progress more rapidly than previously thought
This is a fascinating article that may challenge the conventional thought with regard to the progression rate and risk of cutaneous lupus (discoid lupus erythematosus/DLE) converting to systemic disease. Dermatology offices will often represent the first line of defense for these patients as they present with skin lesions and the diagnosis of DLE is confirmed with biopsy. Dr. Merola specifically focused on the risk of progression to systemic disease among patients with (DLE) suggesting systemic disease can develop within one to two years of initial diagnosis. This patient population will need to be managed collaboratively with our rheumatology colleagues to ensure appropriate counseling and management.
Do you refer all patients diagnosed with DLE for a Rheumatology evaluation?
 
JOB OPPORTUNITIES
 
 
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