Advancing the Art and Science of Prostate Cancer-Related Bone Disease Management

Men with prostate cancer are at significant risk of skeletal complications, including fracture, as a result of prostate cancer-related bone loss and bone metastases. The risk of bone loss and fracture in men with prostate cancer further increases with the use of androgen deprivation therapy (ADT). Prostate cancer frequently metastasizes to bone, which also presents a major challenge. Bone density preservation should be considered a pivotal objective in patients with cancer.

This activity presents information on the clinical impact of bone loss and fracture on men with prostate cancer, provides evidence-based recommendations for the treatment and prevention of bone loss and fracture, and discusses clinical trial data of emerging agents and their potential implications for the future of prostate cancer bone disease management. Upon completion, participants should be able to:
• Describe the impact that bone loss and bone metastases have on the development of skeletal-related events and on quality of life and survival.
• Outline the current standards for the prevention and treatment of prostate cancer-related bone disease.
• Evaluate the clinical data and assess the risks and benefits associated with current and emerging therapies for the treatment and prevention of bone disease in prostate cancer patients.
• Educate patients with clear, concise information on the risks associated with various bone-sparing agents and the risks of complications associated with lack of treatment.
• Formulate and implement a practical plan for overcoming barriers and providing optimal management and prevention of bone loss and bone-related complications.

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