New Strategies to Prevent NSAID-Related Gastropathy
Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for the management of pain and inflammation associated with osteoarthritis, rheumatoid arthritis and other musculoskeletal disorders but they carry a risk for gastrointestinal (GI) toxicity. Although a number of observational studies provide data on risk factors for the development of upper gastrointestinal (GI) complications in NSAID users, there are scant data identifying independent risk factors for the development of ulcers at endoscopy among NSAID users.

This video-based activity discusses gastrointestinal risk factors facing patients on chronic NSAID therapy and presents the combined results from two related clinical research trials. After completing this activity, the participant should be better able to recognize suboptimal or refractory responses to pharmacologic interventions (and modify treatment plans accordingly) and to coordinate a comprehensive care plan to monitor disease progression, safety, risk surveillance, preventive immunizations, and co-morbid health conditions, including collaboration with other health care specialists as appropriate.

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